34370-71-3

Basic information

• Product Name: 2-Propenamide, 3-(4-bromophenyl)-N,N-dimethyl-, (2E)-
• CAS NO: 34370-71-3
• Molecular Formula: C11H12BrNO
• Molecular Weight: 254.126
• Mol File: 34370-71-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, 3-(4-bromophenyl)-N,N-dimethyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, 3-(4-bromophenyl)-N,N-dimethyl-, (2E)-(34370-71-3)
• EPA Substance Registry System: 2-Propenamide, 3-(4-bromophenyl)-N,N-dimethyl-, (2E)-(34370-71-3)

Safety Data

• Hazardous Substances Data: 34370-71-3(Hazardous Substances Data)

Upstream product

• 2680-03-7 N,N-Dimethylacrylamide 
• 586-75-4 4-chlorobenzoyl chloride 
• 137-26-8 Thiram 
• 1200-07-3 trans-4-bromocinnamic acid 
• 127-19-5 N,N-dimethyl acetamide 
• 873-75-6 4-bromobenzenemethanol 
• 1643-30-7 3-(4-bromophenyl)propionic acid 
• 868066-64-2 3-(4-bromophenyl)-N,N-dimethylpropanamide 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 68-12-2 N,N-dimethyl-formamide 
• 5467-74-3 4-Bromophenylboronic acid 

Relevant articles and documents

Synthesis of Cinnamides via Amidation Reaction of Cinnamic Acids with Tetraalkylthiuram Disulfides Under Simple Condition

A facile and efficient methodology for the synthesis of cinnamides has been achieved under metal- and additive-free conditions. This method allows the efficient C–N cross-coupling of diverse cinnamic acids with tetraalkylthiuram disulfides through a simply mixing operation in 1,2-dichloroethane at 100 °C. The protocol provides a direct approach to cinnamides and is featured with readily available starting materials and broad substrate scope, which shows its practical synthetic value in organic synthesis.

Chemoselective α,β-Dehydrogenation of Saturated Amides

We report a method for the selective α,β-dehydrogenation of amides in the presence of other carbonyl moieties under mild conditions. Our strategy relies on electrophilic activation coupled to in situ selective selenium-mediated dehydrogenation. The α,β-unsaturated products were obtained in moderate to excellent yields, and their synthetic versatility was demonstrated by a range of transformations. Mechanistic experiments suggest formation of an electrophilic SeIV species.

Oxidative coupling of alkenes with amides using peroxides: Selective amide C(sp3)-H versus C(sp2)-H functionalization

A new oxidative coupling of unactivated terminal alkenes with amides using peroxides is described, in which mono- and difunctionalization of alkenes are selectively achieved. In this reaction with amides, the chemoselectivity toward the functionalization of the C(sp3)-H bonds adjacent to the nitrogen atom or the functionalization of the carbonyl C(sp2)-H bonds across alkenes relies on the reaction conditions. This journal is