343781-53-3

Usage

Uses

Used in Chemical Synthesis:
2-Pyridinecarboxaldehyde, 3,6-dichlorois used as a building block in the synthesis of various organic compounds. Its unique structure with chlorine atoms allows for versatile chemical reactions, making it a valuable intermediate in the production of a range of chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Pyridinecarboxaldehyde, 3,6-dichlorois utilized for the synthesis of different drugs and their intermediates. Its presence in drug molecules can contribute to the desired pharmacological properties, such as antimicrobial and antifungal activities, enhancing the effectiveness of the final drug products.
Used in Antimicrobial Applications:
2-Pyridinecarboxaldehyde, 3,6-dichlorohas been studied for its potential antimicrobial properties. It can be used as an antimicrobial agent in various applications, such as in the development of new antibiotics or as a component in disinfectants and sanitizers, to combat bacterial infections.
Used in Antifungal Applications:
Similarly, 2-Pyridinecarboxaldehyde, 3,6-dichloro- has also demonstrated antifungal activities, making it a candidate for use in antifungal medications or treatments. It can be incorporated into formulations to target fungal infections, contributing to the development of new antifungal drugs or treatments.
Safety Precautions:
It is important to handle 2-Pyridinecarboxaldehyde, 3,6-dichlorowith care, as it is toxic and may cause skin and eye irritation upon contact. Proper safety measures, such as wearing protective clothing and using appropriate handling equipment, should be taken to minimize the risk of exposure and potential health hazards.

InChI:InChI=1/C6H3Cl2NO/c7-4-1-2-6(8)9-5(4)3-10/h1-3H

Upstream product

• 16110-09-1 2,5 dichloropyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 1702-17-6 Clopyralid 

Downstream Products

• 1699750-95-2 (E)-2-cyano-3-(3,6-dichloropyridin-2-yl)-N-(1-(4-(2-morpholinoethoxy)phenyl)butyl)acrylamide 

Relevant academic research and scientific papers

BENZOTHIOPHENE SULFONAMIDES AND OTHER COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN

The present invention relates to benzothiophene sulfonamides and other compounds that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof.

MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (I) in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

Strategies for the selective functionalization of dichloropyridines at various sites

Whereas 2,3-dichloropyridine and 2,5-dichloro-4-(lithiooxy)-pyridine undergo deprotonation exclusively at the 4- and 2-positions, respectively, optional site selectivity can be implemented with 2,5- and 3,4-dichloropyridine (which are attacked, depending on the choice of the reagents, at either the 4- or 6- and either the 2- and 5-positions, respectively). Upon treatment with lithium diisopropylamide, 2,4-dichloro-3-iodopyridine, 3,5-dichloro-4-bromopyridine and 2,6-dichloro-3-iodopyridine afford 5-, 2- and 4-lithiated intermediates, but the latter isomerize instantaneously to species in which lithium and iodine have swapped places, the driving force being the low basicity of C-Li bonds when flanked by two neighboring halogens.