343783-49-3

Upstream product

• 553679-92-8 2,6-di(tert-butyl)-4-phenyl-6H-1,3,5-oxathiazine S-oxide 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 756841-21-1 2,6-di(tert-butyl)-4-phenyl-6H-1,3,5-oxathiazine 
• 630-19-3 pivalaldehyde 
• 2227-79-4 benzenecarbothioamide 
• 756841-43-7 3-tert-butyl-5-phenyl-3H-[1,2,4]thiaselenazole 

Downstream Products

• 3878-45-3 triphenylphosphine sulfide 
• 100-47-0 benzonitrile 

Relevant academic research and scientific papers

Novel conversion of 6H-1,3,5-oxathiazine S-oxides into 3H-1,2,4-dithiazoles by treating with Lawesson's reagent

Treatment of 6H-1,3,5-oxathiazine S-oxides by Lawesson's reagent (LR) at high temperature furnished 3H-1,2,4-dithiazoles in moderate to good yields. Deoxygenation of 6H-1,3,5-oxathiazine S-oxides was performed by LR in the presence of EtOH.

Synthesis of 1,2,4-dichalcogenazoles by the reaction of 6H-1,3,5-oxachalcogenazines with elemental chalcogen

A series of 1,2,4-dichalcogenazoles were synthesized by the reaction of 6H-1,3,5-oxachalcogenazines with elemental chalcogen through the plausible pathway involving in situ generation of 1,3-chalcogenaza-1,3-butadienes and the subsequent reaction with chalcogen species. Synthetic utilities of 1,2,4-dichalcogenazoles were also explored.

Generation of 1,3-chalcogenaza-1,3-butadienes by thermal cycloreversion of 2,4,6-trisubstituted 6H-1,3,5-oxachalcogenazines

1,3-Thiaza- and 1,3-selenaza- 1,3-butadienes bearing several substituents at the C-2 and C-4 positions were generated through thermal cycloreversion of 6H-1,3,5-oxathiazines or 6H-1,3,5-oxaselenazines, respectively, and the heterodienes were efficiently trapped by using acetylenic dienophiles. When 6H-1,3,5-oxathiazines or 6H-1,3,5-oxaselenazines were heated in the presence of nucleophiles, such as alcohols or thiols, the corresponding 1,4-adducts of the heterodienes with the nucleophiles were obtained in good yields. On the other hand, heating of 6H-1,3,5-oxathiazines or 6H-1,3,5-oxaselenazines in the absence of trapping agents afforded several products which originated from the in situ generated 1,3-chalcogenaza-1,3-butadienes; also the heterodienes were not isolated or observed directly as the monomeric forms at all.