3438-61-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Methylpyrimidin-5-amine is utilized as an intermediate in the synthesis of various pharmaceutical compounds. Its presence in the molecular structure can influence the biological activity and pharmacokinetic properties of the final drug product, making it a crucial component in the development of new medications.
Used in Chemical Synthesis:
In the realm of chemical synthesis, 4-Methylpyrimidin-5-amine serves as a versatile building block for the creation of complex organic molecules. Its reactivity and functional groups allow for a wide range of chemical reactions, facilitating the synthesis of diverse chemical entities.
Used in Organic Reactions:
4-Methylpyrimidin-5-amine is employed as a reagent in various organic reactions, such as condensation, substitution, and rearrangement processes. Its participation in these reactions can lead to the formation of novel compounds with unique properties and potential applications.
Used in Drug Discovery:
4-Methylpyrimidin-5-amine's potential as a precursor in the development of new drugs makes 4-Methylpyrimidin-5-amine a valuable asset in drug discovery research. Its incorporation into drug candidates can contribute to the discovery of innovative therapeutic agents with improved efficacy and selectivity.

Upstream product

• 20090-69-1 2-chloro-4-methyl-5-aminopyrimidine 
• 10034-85-2 hydrogen iodide 
• 13162-26-0 2,4-dichloro-6-methyl-5-nitropyrimidine 

Downstream Products

• 100137-11-9 (4-methyl-pyrimidin-5-yl)-(2-nitro-benzyliden)-amine 
• 272-57-1 1H-pyrazolo[4,3-d]pyrimidine 
• 1192941-21-1 C₂₃H₂₉F₄N₃OSi 
• 1562399-47-6 1,1,1-trifluoro-4-methyl-2-(5H-pyrrolo[3,2-d]pyrimidin-6-ylmethyl)-4-(2-methylphenyl)pentan-2-ol 
• 1439397-25-7 1-[4-(5-methyl-6-phenyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-phenyl]-cyclobutylamine 
• 1439397-29-1 {1-[4-(5-methyl-6-phenyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester 
• 1439397-18-8 1-(4-(6-phenyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl)cyclobutanamine 
• 1439397-23-5 tert-butyl 1-(4-(6-phenyl-5H-pyrrolo[3,2-d]pyrimidin-7-yl)phenyl)cyclobutylcarbamate 
• 1439397-21-3 7-iodo-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine 
• 1439397-27-9 7-iodo-5-methyl-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine 
• 1350352-19-0 6-(2-fluorophenyl)-3-[5-(4-methoxy-2-trifluoromethylphenyl)-[1,3,4]thiadiazol-2-ylmethyl]-3H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid amide 
• 1350352-18-9 6-(2-fluorophenyl)-3-[5-(4-methoxy-2-trifluoromethylphenyl)-[1,3,4]thiadiazol-2-ylmethyl]-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile 
• 1350352-16-7 7-bromo-6-(2-fluorophenyl)-3-[5-(4-methoxy-2-trifluoromethylphenyl)-[1,3,4]thiadiazol-2-ylmethyl]-3H-pyrrolo[3,2-d]pyrimidine 
• 1350351-97-1 3-[5-(4-methoxy-2-trifluoromethylphenyl)-[1,3,4]thiadiazol-2-ylmethyl]-6-(2-fluorophenyl)-3H-pyrrolo[3,2-d]pyrimidine 

Relevant academic research and scientific papers

BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula 1: wherein Het, X, R1 and R2 are as defined herein.