343929-11-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(bromomethyl)-4-chloro-2-iodobenzene is used as an intermediate for the synthesis of various pharmaceuticals. Its presence of halogen atoms and reactive nature allows for participation in substitution and coupling reactions, facilitating the creation of complex molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(bromomethyl)-4-chloro-2-iodobenzene is utilized as a building block for the development of new compounds with pesticidal, herbicidal, or fungicidal properties. Its unique structure and reactivity contribute to the design of effective and targeted agrochemicals.
Used in Dye Industry:
1-(bromomethyl)-4-chloro-2-iodobenzene is employed as an intermediate in the synthesis of dyes due to its reactive halogen atoms and potential for creating a wide range of colored compounds.
Used in Organic Chemistry Research:
1-(bromomethyl)-4-chloro-2-iodobenzene is also used as a building block in organic chemistry research for the creation of more complex molecules. Its unique structure and reactivity make it an important component in the development of new chemical entities with potential applications in various fields.

Upstream product

• 33184-48-4 4-chloro-2-iodotoluene 
• 244104-55-0 (4-chloro-2-iodophenyl)methanol 
• 13421-13-1 4-chloro-2-iodobenzoic acid 

Downstream Products

• 450835-47-9 5-[(4-chloro-2-iodobenzyloxy)-(4-cyanophenyl)methyl]-1-methyl-1H-imidazole 

Relevant academic research and scientific papers

Access to chiral tetrahydrofluorenes through a palladium-catalyzed enantioselective tandem intramolecular Heck/Tsuji-Trost reaction

A palladium-catalyzed enantioselective coupling of 2,5-cyclohexadienyl-substituted aryl iodides and carbon or heteroatom nucleophiles is described. The reaction proceeded via a tandem asymmetric Heck insertion and Tsuji-Trost allylation, enabling the rapi

Stereoretentive Intramolecular Glycosyl Cross-Coupling: Development, Scope, and Kinetic Isotope Effect Study

A series of cyclic C-glycosides were synthesized using the palladium-catalyzed stereoretentive intramolecular glycosylation of aryl iodides by employing a bulky phosphine ligand. A variety of functional groups are tolerated in the reaction, and enantioenr

SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS

The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.

NOVEL COMPOUNDS

Novel Compounds The invention relates to substituted acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.

Design, Synthesis, and Biological Activity of 4-[(4-Cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles as Potent and Selective Farnesyltransferase Inhibitors

A novel series of 4-[(4-cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles have been synthesized as selective farnesyltransferase inhibitors using structure-based design. X-ray cocrystal structures of compound 20-FTase-HFP and A313326-

Farnesyltransferase inhibitors

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.

Farnesyltransferase inhibitors

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.