1-(Bromomethyl)-4-chloro-2-iodobenzene

Base Information

Chemical Name:1-(Bromomethyl)-4-chloro-2-iodobenzene
CAS No.:343929-11-3
Molecular Formula:C₇H₅BrClI
Molecular Weight:331.378
Hs Code.:
DSSTox Substance ID:DTXSID401282782

Synonyms:1-(bromomethyl)-4-chloro-2-iodobenzene;343929-11-3;4-chloro-2-iodobenzyl bromide;SCHEMBL1995097;NHDOHTQSXMMAPT-UHFFFAOYSA-N;DTXSID401282782;MFCD12024995;1-Bromomethyl-4-chloro-2-iodo-benzene;Benzene, 1-(bromomethyl)-4-chloro-2-iodo-;FT-0709049;EN300-7039321

Suppliers and Price of 1-(Bromomethyl)-4-chloro-2-iodobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
4-Chloro-2-iodobenzylbromide
500mg
$ 806.85

Alichem
4-Chloro-2-iodobenzylbromide
250mg
$ 484.80

Total 3 raw suppliers

Chemical Property of 1-(Bromomethyl)-4-chloro-2-iodobenzene

Chemical Property:

Vapor Pressure:0.00122mmHg at 25°C
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:1
Exact Mass:329.83079
Heavy Atom Count:10
Complexity:110

Purity/Quality:: 4-Chloro-2-iodobenzylbromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)I)CBr

Technology Process of 1-(Bromomethyl)-4-chloro-2-iodobenzene

There total 4 articles about 1-(Bromomethyl)-4-chloro-2-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 244104-55-0
(4-chloro-2-iodophenyl)methanol

: 343929-11-3
1-(bromomethyl)-4-chloro-2-iodobenzene

Guidance literature:: With 1H-imidazole; bromine; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b01927

Reference yield:

: 33184-48-4
4-chloro-2-iodotoluene

: 343929-11-3
1-(bromomethyl)-4-chloro-2-iodobenzene

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 48h; Heating;
DOI:10.1021/jm030434f

Reference yield:

: 13421-13-1
4-chloro-2-iodobenzoic acid

: 343929-11-3
1-(bromomethyl)-4-chloro-2-iodobenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: borane-THF / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 2 h / Reflux; Inert atmosphere

2.1: triphenylphosphine; bromine; 1H-imidazole / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; borane-THF; bromine; triphenylphosphine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.orglett.8b01927