3440-49-1Relevant academic research and scientific papers
The p53 stabilizing agent CP-31398 and multi-kinase inhibitors. Designing, synthesizing and screening of styrylquinazoline series
Mularski, Jacek,Malarz, Katarzyna,Pacholczyk, Marcin,Musiol, Robert
, p. 610 - 625 (2019/01/04)
Quinazoline derivatives constitute a large family of small-molecule inhibitors of tyrosine kinases. In the current study, the p53 protein reactivator CP-31398 was tested against a panel of kinases on the assumption that it was structurally similar to othe
Synthesis and properties of quinazoline derivatives containing cymantrenyl group
Kelbysheva,Telegina,Ershova,Strelkova,Ezernitskaya,Nosova,Smol'yakov,Dolgushin,Loim
, p. 327 - 335 (2017/07/11)
The synthesis of new quinazoline derivatives with 2,3- and 4-positioned cymantrenyl fragment is described. Alkylation of 2-substituted quinazolin-4-ones with cymantrenylalkyl bromides on using K2CO3, potassium tert-butoxide, and sodi
Synthesis and photophysical properties of 2-Styrylquinazolin-4-ones
Trashakhova,Nosova,Valova,Slepukhin,Lipunova,Charushin
, p. 753 - 761 (2011/08/22)
Trans-2-Styryl-substituted 3H-, 3-phenyl-, and 3-naphthylquinazolin-4-ones and their 6,7-difl uoro derivatives were synthesized by condensation of appropriate 2-methylquinazolin-4-ones with aromatic aldehydes or by the transformation of the heterocycle of 2-methyl-3,1-benzoxazin-4-one under the action of benzylidenephenylamines. Pleiades Publishing, Ltd., 2011.
Search for substances with antioxidant and antiamnestic activities among 2-substituted 4-(3H)-quinazolones
Kovalenko, Sergey,Belenichev, Igor,Nikitin, Vladislav,Karpenko, Aleksandr
, p. 275 - 279 (2007/10/03)
We have synthesised some of 2-substituted 4-(3H)-quinazolones by the reaction with benzaldehyde and cinnamic aldehyde and their derivatives. It is shown that the intensity of the reaction depends on electrophilic properties of carbonyl compounds and steri
