34403-48-0

Basic information

• Product Name: 4-(Methylaminomethyl)benzonitrile
• Synonyms: 4-(Methylaminomethyl)benzonitrile;N-Methyl-4-cyanobenzylaMine
• CAS NO: 34403-48-0
• Molecular Formula: C₉H₁₀N₂
• Molecular Weight: 146.19
• Product Categories: Polyamines
• Mol File: 34403-48-0.mol
• Article Data: 20

Chemical Properties

• Melting Point: 108-109 °C
• Boiling Point: 257.849 °C at 760 mmHg
• Flash Point: 109.744 °C
• Appearance: /
• Density: 1.04 g/cm³
• Vapor Pressure: 0.014mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.01±0.10(Predicted)
• CAS DataBase Reference: 4-(Methylaminomethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Methylaminomethyl)benzonitrile(34403-48-0)
• EPA Substance Registry System: 4-(Methylaminomethyl)benzonitrile(34403-48-0)

Safety Data

• Hazardous Substances Data: 34403-48-0(Hazardous Substances Data)

Usage

Chemical Properties

Colorless Liquid

InChI:InChI=1/C9H10N2/c1-11-7-9-4-2-8(6-10)3-5-9/h2-5,11H,7H2,1H3

Upstream product

• 2083-91-2 N,N-Dimethyltrimethylsilylamine 
• 623-00-7 4-bromobenzenecarbonitrile 
• 105-07-7 4-cyanobenzaldehyde 
• 74-89-5 methylamine 
• 7487-88-9 magnesium sulfate 
• 118964-95-7 4-((methylimino)methyl)benzonitrile 
• 17201-43-3 4-cyanobenzyl bromide 
• 118964-95-7 4-[(Z)-Methyliminomethyl]-benzonitrile 
• 35525-86-1 4-cyano-N,N-dimethylbenzylamine 
• 874-86-2 4-cyanobenzyl chloride 

Downstream Products

• 441295-89-2 [(4-cyanophenyl)methyl]methylcarbamic acid phenylmethyl ester 
• 1123813-07-9 (R)-N₂-(4-cyanobenzyl)-N₁-(4-chlorophenyl)-N₂-methylpyrrolidine-1,2-dicarboxamide 
• 633698-48-3 2-[4-[[[[2-[[(2,4-dichloro-3-methylphenyl)sulfonyl]methylamino]ethoxy]acetyl]methylamino]methyl]phenyl]-4,5-dihydro-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633696-69-2 2-[4-[[[(2E)-4-[[(2,4-dichloro-3-methylphenyl)sulfonyl]methylamino]-1-oxo-2-butenyl]methylamino]methyl]phenyl]-4,5-dihydro-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633696-68-1 2-[4-[[[3-[[(2,4-dichloro-3-methylphenyl)sulfonyl]methylamino]-1-oxopropyl]methylamino]methyl]phenyl]-4,5-dihydro-1-H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-88-1 2-[4-[[[[2-[[(2,6-difluorophenyl)sulfonyl]methylamino]ethoxy]acetyl]methylamino]methyl]phenyl]-4,5-dihydro-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-85-8 2-[4-[[[[2-[[(3-chloro-2-methylphenyl)sulfonyl]methylamino]ethoxy]acetyl]methylamino]methyl]phenyl]-4,5-dihydro-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-83-6 2-[4-[[[[2-[[(2-cyanophenyl)sulfonyl]methylamino]ethoxy]acetyl]methylamino]methyl]phenyl]-4,5-dihydro-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-76-7 4,5-dihydro-2-[4-[[methyl[[2-[methyl[[2-(trifluoromethyl)phenyl]sulfonyl]amino]ethoxy]acetyl]amino]methyl]phenyl]-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-77-8 4,5-dihydro-2-[4-[[[[2-[[(4-methoxy-2,6-dimethylphenyl)sulfonyl]methylamino]ethoxy]acetyl]methylamino]methyl]phenyl]-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-75-6 4,5-dihydro-2-[4-[[methyl[[2-(methylamino)ethoxy]acetyl]amino]methyl]phenyl]-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 633698-74-5 2-[4-(2,8-dimethyl-3,9-dioxo-11-phenyl-5,10-dioxa-2,8-diazaundec-1-yl)phenyl]-4,5-dihydro-1H-imidazole-1-carboxylic acid 1,1-dimethylethyl ester 
• 31417-69-3 1-(4-(aminomethyl)phenyl)-N-methylmethanamine 

Relevant articles and documents

SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI

The present invention relates to novel trifluoromethyloxadiazoles of the formula (I) or an N-oxide and/or their agriculturally useful salts and to their use for controlling phytopathogenic fungi, or to a method for combating phytopathogenic harmful fungi,

tert-Butoxy-Radical-Promoted α-Arylation of Alkylamines with Aryl Halides

In the presence of a tert-butoxy radical precursor, the reaction of alkylamines with aryl halides was found to give α-arylated alkylamines through homolytic aromatic substitution of the halogen atoms.

Chemoselective reductive nucleophilic addition to tertiary amides, secondary amides, and N-methoxyamides

As the complexity of targeted molecules increases in modern organic synthesis, chemoselectivity is recognized as an important factor in the development of new methodologies. Chemoselective nucleophilic addition to amide car-bonyl centers is a challenge because classical methods require harsh reaction conditions to overcome the poor elec-trophilicity of the amide carbonyl group. We have successfully developed a reductive nucleophilic addition of mild nu-cleophiles to tertiary amides, secondary amides, and N-methoxyamides that uses the Schwartz reagent [Cp2ZrHCl]. The reaction took place in a highly chemoselective fashion in the presence of a variety of sensitive functional groups, such as methyl esters, which conventionally require protection prior to nucleophilic addition. The reaction will be applicable to the concise synthesis of complex natural alkaloids from readily available amide groups.