344330-65-0Relevant academic research and scientific papers
NEW LOW-VALENT TITANIUM CATALYZED REACTION OF CHLORODIFLUOROMETHYL KETONES LEADING TO α,α-DIFLUORINATED β-HYDROXY KETONES
Ishihara, Takashi,Yamanaka, Tohru,Ando, Teiichi
, p. 1165 - 1168 (2007/10/02)
Various chlorodifluoromethyl ketones underwent the aldol-type reaction with aldehydes or ketones by the action of titanium tetrachloride and zinc reagent in tetrahydrofuran at room temperature to give moderate to good yields of α,α-difluorinated β-hydroxy
