344459-54-7

Basic information

• Product Name: N-[3-[4-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluorophenyl]-2-oxooxazolidin-5(S)-ylmethyl]acetamide
• Synonyms: RWJ-337813
• CAS NO: 344459-54-7
• Molecular Formula: C₁₉H₁₉FN₄O₃
• Molecular Weight: 370.38668
• Mol File: 344459-54-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-[3-[4-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluorophenyl]-2-oxooxazolidin-5(S)-ylmethyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-[4-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluorophenyl]-2-oxooxazolidin-5(S)-ylmethyl]acetamide(344459-54-7)
• EPA Substance Registry System: N-[3-[4-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluorophenyl]-2-oxooxazolidin-5(S)-ylmethyl]acetamide(344459-54-7)

Safety Data

• Hazardous Substances Data: 344459-54-7(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 344460-47-5 5-aminomethyl-3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-oxazolidin-2-one 
• 344460-46-4 5-azidomethyl-3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-oxazolidin-2-one 
• 344460-45-3 methanesulfonic acid 3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl ester 
• 344460-43-1 [4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-carbamic acid benzyl ester 
• 344459-52-5 (5R)-3-[4-(5,7-Dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone 
• 147740-02-1 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride salt 
• 344460-40-8 6,7-Dihydro-6-(2-fluoro-4-nitrophenyl)-5H-pyrrolo[3,4-b]pyridine 
• 344460-41-9 6,7-Dihydro-6-(2-fluoro-4-aminophenyl)-5H-pyrrolo[3,4-b]pyridine 
• 369-34-6 3,4-difluoronitrobenzene 
• 147740-01-0 ethyl 5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements

A series of pyrrolopyridine-substituted oxazolidinones containing various C-5 acetamide isosteres was synthesized and the structure-antibacterial activity relationships determined against a representative panel of susceptible and resistant Gram-positive b

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

A novel series of oxazolidinones containing a pyrroloaryl substituent was synthesized and screened against a representative panel of susceptible and resistant Gram-positive bacteria. Several members of this series were found to have antibacterial activity comparable to or better than linezolid.

Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods

Bicyclic heterocyclic substituted phenyl oxazolidinone compounds of the formula: wherein Y is a radical of the formulae II or III: in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.