344552-59-6

Upstream product

• 3319-03-7 2-dimethylamino-1-phenyl-ethanone 
• 40178-28-7 1,1-dimethyl-1-phenacylhydrazinium bromide 
• 56955-32-9 (R)-(+)-NN-dimethyl-N-phenacyl-1-phenylethylammonium bromide 
• 87305-45-1 (R,S)-NN-dimethyl-N-phenacyl-1-p-methoxyphenylethylammonium bromide 
• 42142-22-3 (R,S)-NN-dimethyl-1-p-nitrophenylethylamine 
• 70-11-1 α-bromoacetophenone 
• 50640-96-5 (R,S)-NN-dimethyl-1-p-methoxyphenylethylamine 
• 19342-01-9 (S)-N,N-dimethyl-1-phenylethylamine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 124-40-3 dimethyl amine 
• 959-28-4 1,4-diphenylbut-2-ene-1,4-dione 
• 87258-58-0 (R,S)-NN-dimethyl-N-phenacyl-1-p-nitrophenylethylammonium bromide 
• 25241-18-3 anhydro 

Downstream Products

• 56955-30-7 Dimethylaminophenacylradikal 

Relevant academic research and scientific papers

The Reaction of 1,1-Dimethyl-1-Phenacylhydrazinium Bromide with Aqueous Sodium Hydroxide

The reaction of 1,1-dimethyl-1-phenacylhydrazinium bromide with 1 M aqueous sodium hydroxide give benzoic acid, 3-phenyl-1-methylpyrazole, 5-benzoyl-3-phenyl-1-methylpyrazole, and benzonitrile as the major components; the expected product, 2-benzoyl-5-phenylimidazole was formed in only small amounts.Mechanisms to rationalize the formation of the major products are discussed.

Base Catalysed Rearrangements involving Ylide Intermediates. Part 15. The Machanism of the Stevens Rearrangement

The Stevens rearrangement of acyl-stabilised ammonium ylides has been investigated with regard to stereoselectivity, intramolecularity and the formation of products in addition to the rearrangement product.A detailed study of the effects of reaction conditions upon the rearrangement of the ylide derived from the salt (13) has shown that the stereoselectivity (retention of the configuration of the chiral migrating group) and intramolecularity decrease as solvent viscosity decreases.The rearrangement of the salt (13) in water at 0 deg C is essentially intramolecular with virtually complete retention of the configuration of the migrating group.These results, together with the isolation of products that can be rationalised on the basis of random free-radical coupling, indicate that the rearrangement of acyl-stabilised ammonium ylides normally involves a radical pair mechanism.