42142-22-3

Basic information

• Product Name: (R,S)-NN-dimethyl-1-p-nitrophenylethylamine
• Synonyms: (R,S)-NN-dimethyl-1-p-nitrophenylethylamine
• CAS NO: 42142-22-3
• Molecular Weight: 194.233
• Mol File: 42142-22-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R,S)-NN-dimethyl-1-p-nitrophenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R,S)-NN-dimethyl-1-p-nitrophenylethylamine(42142-22-3)
• EPA Substance Registry System: (R,S)-NN-dimethyl-1-p-nitrophenylethylamine(42142-22-3)

Safety Data

• Hazardous Substances Data: 42142-22-3(Hazardous Substances Data)

Upstream product

• 19935-81-0 4-nitro-(1-bromoethyl)benzene 
• 124-40-3 dimethyl amine 
• 50-00-0 formaldehyd 
• 42142-15-4 1-(4-nitro-phenyl)-ethylamine 

Downstream Products

• 91800-14-5 4-(1-(dimethylamino)ethyl)benzenamine 
• 344552-59-6 2,3-bis(dimethylamino)-1,4-diphenyl-1,4-butanedione 
• 24904-79-8 (+/-)-2,3-di-p-nitrophenylbutane 
• 24904-79-8 meso-2,3-di-p-nitrophenylbutane 
• 87258-58-0 (R,S)-NN-dimethyl-N-phenacyl-1-p-nitrophenylethylammonium bromide 

Relevant articles and documents

PYRAZOLE DERIVATIVES AS ANTI-PLATELET AND ANTI-THROMBOTIC AGENTS

This invention relates to novel compounds of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof wherein Y, R1 through R9, and X1 through X7 are as defined in the specification, pharmaceutical compositions containing said compounds useful as P2Y1 antagonists, and to methods of treating thromboembolic disorders.

Base Catalysed Rearrangements involving Ylide Intermediates. Part 15. The Machanism of the Stevens Rearrangement

The Stevens rearrangement of acyl-stabilised ammonium ylides has been investigated with regard to stereoselectivity, intramolecularity and the formation of products in addition to the rearrangement product.A detailed study of the effects of reaction conditions upon the rearrangement of the ylide derived from the salt (13) has shown that the stereoselectivity (retention of the configuration of the chiral migrating group) and intramolecularity decrease as solvent viscosity decreases.The rearrangement of the salt (13) in water at 0 deg C is essentially intramolecular with virtually complete retention of the configuration of the migrating group.These results, together with the isolation of products that can be rationalised on the basis of random free-radical coupling, indicate that the rearrangement of acyl-stabilised ammonium ylides normally involves a radical pair mechanism.