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1,2,3-Triazolo[5,1-a]isoquinoline is a heterocyclic compound characterized by a fused ring structure consisting of a triazole and an isoquinoline. [1,2,3]Triazolo[5,1-a]isoquinoline is of interest in medicinal chemistry due to its potential as a scaffold for the development of new drugs. The triazole ring, with its nitrogen-rich structure, can form strong hydrogen bonds and coordinate with metal ions, making it a versatile building block for various biologically active molecules. The isoquinoline moiety, on the other hand, is known for its aromaticity and stability, which can contribute to the overall pharmacokinetic properties of the molecule. Together, the 1,2,3-triazolo[5,1-a]isoquinoline structure offers a platform for the design of compounds with specific binding affinities and therapeutic effects, particularly in the areas of oncology and central nervous system disorders.

34456-69-4

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34456-69-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 34456-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,4,5 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 34456-69:
(7*3)+(6*4)+(5*4)+(4*5)+(3*6)+(2*6)+(1*9)=124
124 % 10 = 4
So 34456-69-4 is a valid CAS Registry Number.

34456-69-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name triazolo[5,1-a]isoquinoline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:34456-69-4 SDS

34456-69-4Relevant academic research and scientific papers

AlCl3-promoted three-component cascade reaction for rapid access to [1,2,3]triazolo[5,1-a]isoquinolines

Wu, Yangang,Meng, Yonggang,Liu, Zibo,Zhang, Mengge,Song, Chuanjun

, (2019/11/11)

Novel AlCl3-promoted, three component cascade Henry reaction-triazole formation-intramolecular 6-endo-dig cyclization reactions between 2-alkynylaryl aldehydes, nitroalkanes, and sodium azide for the assembly of [1,2,3]triazolo[5,1-a]isoquinolines have been developed. Further transformations of representative [1,2,3]triazolo[5,1-a]isoquinolines are also described.

Synthesis of novel triazolopyridylboronic acids and esters. Study of potential application to Suzuki-type reactions

Abarca, Belén,Ballesteros, Rafael,Blanco, Fernando,Bouillon, Alexandre,Collot, Valérie,Domínguez, José-Reynaldo,Lancelot, Jean-Charles,Rault, Sylvain

, p. 4887 - 4893 (2007/10/03)

This paper describes a general method for the synthesis of novel [1,2,3]triazolo[1,5-a]pyridylboronic acids and esters, and the first results on Suzuki cross-coupling reactions with these new compounds and [1,2,3]triazolo[5,1-a]isoquinolylboronic acid, re

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