34457-01-7

Basic information

• Product Name: Benzene, 1-(1-bromoethyl)-2-methyl-
• CAS NO: 34457-01-7
• Molecular Formula: C9H11Br
• Molecular Weight: 199.09
• Mol File: 34457-01-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-bromoethyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-bromoethyl)-2-methyl-(34457-01-7)
• EPA Substance Registry System: Benzene, 1-(1-bromoethyl)-2-methyl-(34457-01-7)

Safety Data

• Hazardous Substances Data: 34457-01-7(Hazardous Substances Data)

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 577-16-2 2-Methylacetophenone 
• 7287-82-3 1-O-tolyl-ethanol 

Downstream Products

• 128517-18-0 1-phenyl-3-(o-tolyl)butan-1-one 

Relevant articles and documents

In Situ Generated Gold Nanoparticles on Active Carbon as Reusable Highly Efficient Catalysts for a Csp3 ?Csp3 Stille Coupling

Gold nanoparticle catalysts are important in many industrial production processes. Nevertheless, for traditional Csp2-Csp2 cross-coupling reactions they have been rarely used and Pd catalysts usually give a superior performance. Herein we report that in situ formed gold metal nanoparticles are highly active catalysts for the cross coupling of allylstannanes and activated alkylbromides to form Csp3-Csp3 bonds. Turnover numbers up to 29 000 could be achieved in the presence of active carbon as solid support, which allowed for convenient catalyst recovery and reuse. The present study is a rare case where a gold metal catalyst is superior to Pd catalysts in a cross-coupling reaction of an organic halide and an organometallic reagent.

PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS

The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

NOVEL TRPV3 MODULATORS

Disclosed herein are modulators of TRPV3 of formula (I) wherein G1, X1, X2, X3, X4, X5, G2, Z1, Ra, Rb, u, and p are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.