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4-Bromo-5-methylresorcinol, also known as 4-Bromo-5-methylbenzene-1,3-diol, is an organic compound characterized by the presence of a bromine atom at the 4th position and a methyl group at the 5th position on a resorcinol backbone. It exhibits unique chemical properties due to its structural features, making it a versatile compound for various applications.

3446-04-6

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3446-04-6 Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-5-methylresorcinol is used as an intermediate in the synthesis of phenanthrenes, which are compounds known for their antioxidant and anti-inflammatory activities. These properties make them valuable in the development of drugs targeting conditions that involve oxidative stress and inflammation.
Used in Chemical Synthesis:
In the field of organic chemistry, 4-Bromo-5-methylresorcinol serves as a key building block for the synthesis of various complex organic molecules. Its unique structural features allow for selective functionalization and modification, making it a useful starting material for the creation of novel compounds with potential applications in various industries.
Used in Research and Development:
4-Bromo-5-methylresorcinol is also utilized in research and development settings, where it can be employed to study the effects of structural modifications on the properties and reactivity of resorcinol-based compounds. This knowledge can be applied to design and develop new molecules with improved or novel functionalities.

Check Digit Verification of cas no

The CAS Registry Mumber 3446-04-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,4 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3446-04:
(6*3)+(5*4)+(4*4)+(3*6)+(2*0)+(1*4)=76
76 % 10 = 6
So 3446-04-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BrO2/c1-4-2-5(9)3-6(10)7(4)8/h2-3,9-10H,1H3

3446-04-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-5-methylbenzene-1,3-diol

1.2 Other means of identification

Product number -
Other names 2-Brom-3.5-dihydroxy-toluol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3446-04-6 SDS

3446-04-6Relevant academic research and scientific papers

SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF

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Page/Page column 68-69, (2021/07/02)

The present disclosure relates to substituted hydroxystilbene compounds and derivatives, specifically 2-substituted hydroxystilbene compounds and derivatives, the synthesis of such compounds and their use in therapy.

Lysilactones A-C, three 6H-dibenzo[b,d]pyran-6-one glycosides from Lysimachia clethroides, total synthesis of Lysilactone A

Liang, Dong,Luo, Huan,Liu, Yan-Fei,Hao, Zhi-You,Wang, Yan,Zhang, Chun-Lei,Zhang, Qing-Jian,Chen, Ruo-Yun,Yu, De-Quan

, p. 2093 - 2097 (2013/03/13)

Three 6H-dibenzo[b,d]pyran-6-one glycosides named lysilactones A-C (1-3) were isolated from the aerial parts of Lysimachia clethroides. Their structures were elucidated using spectroscopic analysis and chemical evidence. This is the first report of 6H-dib

Regioselective synthesis of phenanthrenes and evaluation of their anti-oxidant based anti-inflammatory potential

Kanekar, Yogesh,Basha, Khalander,Duche, Sharad,Gupte, Rajan,Kapat, Arnab

supporting information, p. 454 - 463 (2013/10/01)

Regioselective synthesis of 9,10-Dihydro-2,5-Dimethoxyphenanthrene-1,7-diol (1) and 9,10-Dihydro-2,7-Dimethoxyphenanthrene-1,5-diol (2) was achieved using regioselective methylation, Wittig reaction, intramolecular cyclization and hydrogenation as key ste

Studies of (Pd0-mediated) stille cross-coupling reactions of thiophenestannane with aryl halide derivatives

Hamad Elgazwy, Abdel-Sattar S.

, p. 131 - 143 (2007/10/03)

Stille (arylstannane) conditions used Pd0-mediated cross-coupling reactions for preparation of thiophene/aryl analogs. Different arylhalides were compared when coupled with heterometal (thiophenestannane) system. Comparable yields have now been obtained by Stille (arylstannane) couplings with different reactivity of arylhalides.

Halogenation Using Quaternary Ammonium Polyhalides. IV. Selective Bromination of Phenols by Use of Tetraalkylammonium Tribromides

Kajigaeshi, Shoji,Kakinami, Takaaki,Okamoto, Tsuyoshi,Nakamura, Hiroko,Fujikawa, Masahiro

, p. 4187 - 4189 (2007/10/02)

Reaction of phenols with calculated amounts of benzyltrimethylammonium tribromide or tetrabutylammonium tribromide in dichloromethane-methanol for 0.5-1 h under mild conditions gave, selectively, the objective mono-, di-, or tribromophenols in good yields.

Course of Aromatisation of 5-Alkyl/aryl-2-bromocyclohex-2-en-3-ol-1-ones to Corresponding 5-Alkyl/arylresorcinols

Chandrasekharan, V.,Unnikrishnan, P.,Shah, G. D.,Bhattacharyya, S. C.

, p. 1052 - 1055 (2007/10/02)

5-Alkyl/aryl-2-bromocyclohex-2-en-3-ol-1-ones on heating undergo aromatisation through dehydrobromination to the corresponding 5-substituted resorcinols.During the course of aromatisation of 2-bromo-5-methylcyclohex-2-en-3-ol-1-one (I) and 5-n-amyl-2-bromocyclohex-2-en-3-ol-1-one (II) a few intermediates have been isolated and characterised as IV, V, VI, VIII and IX.Similar studies on 2-bromo-5-phenylcyclohex-2-en-3-ol-1-one yields two structurally different products, one with no bromine (XI) and the other with bromine in position-2 (XII), besides 5-phenylresorcinol (XIII).

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