34486-23-2

Basic information

• Product Name: 6-Chloro-4-(trifluoromethyl)pyridin-2-amine
• Synonyms: 6-chloro-4-(trifluoromethyl)pyridin-2-amine;6-Chloro-4-trifluoromethyl-pyridin-2-ylamine;6-Chloro-4-(trifluoroMethyl)pyridine-2-aMine;2-Amino-6-chloro-4-(trifluoromethyl)pyridine 95+%;6-Chloro-4-(trifluoromethyl)pyridin-2-amine, 2-Amino-6-chloro-alpha,alpha,alpha-trifluoro-4-picoline
• CAS NO: 34486-23-2
• Molecular Formula: C₆H₄ClF₃N₂
• Molecular Weight: 196.56
• Mol File: 34486-23-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 252.2 °C at 760 mmHg
• Flash Point: 106.3 °C
• Appearance: /
• Density: 1.507 g/cm³
• Vapor Pressure: 0.0196mmHg at 25°C
• Refractive Index: 1.501
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 6-Chloro-4-(trifluoromethyl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-4-(trifluoromethyl)pyridin-2-amine(34486-23-2)
• EPA Substance Registry System: 6-Chloro-4-(trifluoromethyl)pyridin-2-amine(34486-23-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 34486-23-2(Hazardous Substances Data)

Usage

General Description

6-Chloro-4-(trifluoromethyl)pyridin-2-amine is a chemical compound consisting of a pyridine ring with a chlorine atom at position 6 and a trifluoromethyl group at position 4. 6-Chloro-4-(trifluoromethyl)pyridin-2-amine is an amine, as indicated by the presence of an amino group at position 2 of the pyridine ring. It is primarily used in the pharmaceutical industry for the synthesis of various drugs and active pharmaceutical ingredients. Additionally, it has potential applications in agrochemicals, dyes, and other industrial processes. The presence of the trifluoromethyl group makes this compound useful in medicinal chemistry for the development of drugs with improved properties, such as metabolic stability and enhanced bioavailability. Overall, 6-Chloro-4-(trifluoromethyl)pyridin-2-amine is a versatile and important chemical compound with various potential applications in different industries.

InChI:InChI=1/C6H4ClF3N2/c7-4-1-3(6(8,9)10)2-5(11)12-4/h1-2H,(H2,11,12)

Upstream product

• 1336-21-6 ammonium hydroxide 
• 39890-98-7 2,6-dichloro-4-(trifluoromethyl)pyridine 
• 81565-18-6 2-chloro-4-trifluoromethyl pyridine 

Downstream Products

• 165385-89-7 6-methyl-4-(trifluoromethyl)pyridin-2-amine 
• 1452573-03-3 6-(2-phenylethynyl)-4-(trifluoromethyl)pyridin-2-amine 
• 1452572-43-8 2-(methylamino)-N-[6-(2-phenylethynyl)-4-(trifluoromethyl)pyridin-2-yl]propanamide 
• 130171-52-7 4-(trifluoromethyl)pyridine-2,6-diamine 

Relevant articles and documents

BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF

The present disclosure is directed to modulators of SOS1 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.

1-((1H-PYRAZOL-4-YL)METHYL)-3-(PHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS GPR139 ANTAGONISTS FOR THE TREATMENT OF E.G. DEPRESSION

The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease

HETEROCYCLIC COMPOUND

The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.