34486-23-2

Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-4-(trifluoromethyl)pyridin-2-amine is utilized as a key intermediate in the synthesis of various drugs and active pharmaceutical ingredients. Its presence of the trifluoromethyl group contributes to the development of drugs with improved metabolic stability and enhanced bioavailability, making it a valuable component in medicinal chemistry.
Used in Agrochemicals:
In the agrochemical industry, 6-Chloro-4-(trifluoromethyl)pyridin-2-amine serves as a building block for the creation of new agrochemicals, potentially leading to the development of more effective and safer pesticides and other agricultural products.
Used in Dyes:
6-Chloro-4-(trifluoromethyl)pyridin-2-amine is employed as a precursor in the production of dyes, where its unique chemical structure can contribute to the creation of dyes with specific color properties and improved performance characteristics.
Used in Other Industrial Processes:
Beyond the primary industries mentioned, 6-Chloro-4-(trifluoromethyl)pyridin-2-amine also finds applications in various other industrial processes, where its chemical properties can be harnessed for specific technical or manufacturing purposes.

InChI:InChI=1/C6H4ClF3N2/c7-4-1-3(6(8,9)10)2-5(11)12-4/h1-2H,(H2,11,12)

Upstream product

• 1336-21-6 ammonium hydroxide 
• 39890-98-7 2,6-dichloro-4-(trifluoromethyl)pyridine 
• 81565-18-6 2-chloro-4-trifluoromethyl pyridine 

Downstream Products

• 1452572-43-8 2-(methylamino)-N-[6-(2-phenylethynyl)-4-(trifluoromethyl)pyridin-2-yl]propanamide 
• 1452573-03-3 6-(2-phenylethynyl)-4-(trifluoromethyl)pyridin-2-amine 
• 165385-89-7 6-methyl-4-(trifluoromethyl)pyridin-2-amine 
• 130171-52-7 4-(trifluoromethyl)pyridine-2,6-diamine 

Relevant academic research and scientific papers

BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF

The present disclosure is directed to modulators of SOS1 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.

EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS

The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. For Formula I compounds X1, X2, X3, X4, X5, X6, Q, L1, L2, Y, R1, R2, R3, R4, R5, R6, R7, R8 and rings A, B and C are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4e and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.

1-((1H-PYRAZOL-4-YL)METHYL)-3-(PHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS GPR139 ANTAGONISTS FOR THE TREATMENT OF E.G. DEPRESSION

The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease

COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS

The invention relates to a compound of Formula I, pharmaceutical compositions comprising a compound of Formula I, and pharmaceutically acceptable slats thereof, pharmaceutical compositions comprising such compounds and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of Formula I to a subject in need thereof.

HETEROCYCLIC COMPOUND

The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.

METHOD FOR PRODUCING 2-AMINO-4-(TRIFLUOROMETHYL)PYRIDINE

The present invention relates to a process for producing a 2-amino-4-trifluoromethylpyridine. Specifically, the present invention provides a process for producing a compound represented by the formula (I) or a salt thereof: (in the formula, X1 is the same as X1 in the formula (II) below), which includes allowing a compound represented by the formula (II): (in the formula, each of X1 and X2 is independently a chlorine atom or a bromine atom) to react with ammonia in the presence of a hydrophilic ether; and also a process for producing 2-amino-4-trifluoromethyl pyridine or a salt thereof, which comprises subjecting the compound of the formula (I) as produced by the foregoing process to dehalogenation,

TRIAZOLOPYRIDINE COMPOUNDS AND THEIR USE AS ASK INHIBITORS

The present invention relates to triazolopyridine compounds according to Formula (I), their use as medicament, for treating autoimmune disorders, inflammatorydiseases, cardiovascular disceases and/or neurodegenerative diseases and a process for their preparation.

NEW PYRIDINES AS FBPASE INHIBITORS FOR TREATMENT OF DIABETES

Compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof wherein the residues have the significance given in claim 1 and which can be used in the form of pharmaceutical compositions.