34489-85-5

Basic information

• Product Name: 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE
• Synonyms: 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE;shikonofuran A
• CAS NO: 34489-85-5
• Molecular Formula: C₁₃H₁₁BrN₂O
• Molecular Weight: 291.14
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 34489-85-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE(34489-85-5)
• EPA Substance Registry System: 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE(34489-85-5)

Safety Data

• Hazardous Substances Data: 34489-85-5(Hazardous Substances Data)

Usage

General Description

2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE is a chemical compound with the molecular formula C13H11BrN2O. It belongs to the class of benzamides and contains an amine group and a bromophenyl group. 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE is used in pharmaceutical research and development as it has potential bioactive properties. It has been studied for its role as an inhibitor of certain enzymes and as a potential drug candidate for various medical conditions. Its unique structure and properties make it a valuable chemical for medicinal and biological research.

Upstream product

• 118-48-9 isatoic anhydride 
• 615-36-1 2-bromoaniline 
• 118-92-3 anthranilic acid 
• 34489-84-4 2-Nitro-benzoesaeure-<2-brom-anilid> 
• 610-14-0 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 21563-73-5 2-aminobenzoyl chloride 

Downstream Products

• 5814-41-5 5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one 
• 4260-20-2 2-methyl-3-(o-bromophenyl)-4(3H)-quinazolinone 
• 34489-86-6 3-(2-bromophenyl)benzo[d][1,2,3]triazin-4(3H)-one 
• 1429192-28-8 C₁₉H₁₅BrN₂OS 

Relevant articles and documents

NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides

An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramolecular cyclization.

CuI/l-proline-catalyzed intramolecular aryl amination: An efficient route for the synthesis of 1,4-benzodiazepinones

An effective protocol for the synthesis of potentially bioactive benzo[e]chromeno[6,5-b][1,4]diazepine-3,8(7H,13H)-dione and dibenzo[b,e][1,4] diazepin-11(10H)-one derivatives in good to excellent yields has been achieved by CuI/l-Proline catalyzed coupling reaction as the key step. The methodology offers clean reaction conditions and easy isolation of the products in 61-92% yields.