34489-85-5

Usage

Uses

Used in Pharmaceutical Research and Development:
2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE is employed as a research chemical for its potential bioactive properties. It is particularly valuable in the discovery and development of new pharmaceuticals due to its capacity to inhibit certain enzymes, which may contribute to the treatment of various medical conditions.
Used in Enzyme Inhibition Studies:
In the field of medicinal chemistry, 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE is used as an enzyme inhibitor. Its specific interactions with target enzymes can provide insights into disease mechanisms and aid in the design of more effective therapeutic agents.
Used as a Potential Drug Candidate:
Owing to its bioactive nature, 2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE is considered a potential drug candidate for various medical conditions. Its development and optimization in preclinical and clinical studies may lead to novel treatments for unmet medical needs.
Used in Medicinal and Biological Research:
2-AMINO-N-(2-BROMOPHENYL)BENZAMIDE's unique structure and properties make it a valuable tool in medicinal and biological research. It can be utilized to probe biological pathways, evaluate the efficacy of drug candidates, and understand the mechanisms of action in drug discovery processes.

Upstream product

• 118-48-9 isatoic anhydride 
• 615-36-1 2-bromoaniline 
• 21563-73-5 2-aminobenzoyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 610-14-0 2-nitrobenzyl chloride 
• 34489-84-4 2-Nitro-benzoesaeure-<2-brom-anilid> 
• 118-92-3 anthranilic acid 

Downstream Products

• 5814-41-5 5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one 
• 4260-20-2 2-methyl-3-(o-bromophenyl)-4(3H)-quinazolinone 
• 34489-86-6 3-(2-bromophenyl)benzo[d][1,2,3]triazin-4(3H)-one 
• 1429192-28-8 C₁₉H₁₅BrN₂OS 

Relevant academic research and scientific papers

NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides

An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramolecular cyclization.

Deep eutectic solvent mediated synthesis of quinazolinones and dihydroquinazolinones: Synthesis of natural products and drugs

A mild and greener protocol was developed to synthesize substituted quinazolinones and dihydroquinazolinones via deep eutectic solvent (DES) mediated cyclization with a series of aliphatic, aromatic, and heteroaromatic aldehydes in good to excellent yields. This greener strategy was further utilised to synthesize various quinazolinone natural products and drugs.

CuI/l-proline-catalyzed intramolecular aryl amination: An efficient route for the synthesis of 1,4-benzodiazepinones

An effective protocol for the synthesis of potentially bioactive benzo[e]chromeno[6,5-b][1,4]diazepine-3,8(7H,13H)-dione and dibenzo[b,e][1,4] diazepin-11(10H)-one derivatives in good to excellent yields has been achieved by CuI/l-Proline catalyzed coupling reaction as the key step. The methodology offers clean reaction conditions and easy isolation of the products in 61-92% yields.