3449-42-1

Basic information

• Product Name: diethyl 2,6-dihydroxy-4-(4-methoxyphenyl)-2,6-bis(trifluoromethyl)tetrahydro-2H-pyran-3,5-dicarboxylate
• Synonyms: 2H-Pyran-3,5-dicarboxylic acid, tetrahydro-2,6-dihydroxy-4-(4-methoxyphenyl)-2,6-bis(trifluoromethyl)-, diethyl ester
• CAS NO: 3449-42-1
• Molecular Formula: C₂₀H₂₂F₆O₈
• Molecular Weight: 504.3743
• Mol File: 3449-42-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 505.9°C at 760 mmHg
• Flash Point: 259.7°C
• Density: 1.437g/cm³
• Vapor Pressure: 4.69E-11mmHg at 25°C
• Refractive Index: 1.479
• CAS DataBase Reference: diethyl 2,6-dihydroxy-4-(4-methoxyphenyl)-2,6-bis(trifluoromethyl)tetrahydro-2H-pyran-3,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2,6-dihydroxy-4-(4-methoxyphenyl)-2,6-bis(trifluoromethyl)tetrahydro-2H-pyran-3,5-dicarboxylate(3449-42-1)
• EPA Substance Registry System: diethyl 2,6-dihydroxy-4-(4-methoxyphenyl)-2,6-bis(trifluoromethyl)tetrahydro-2H-pyran-3,5-dicarboxylate(3449-42-1)

Safety Data

• Hazardous Substances Data: 3449-42-1(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 

Relevant articles and documents

Synthesis of 2,6-bis(fluoroalkyl)-2,6-dihydroxytetrahydro-2H-pyran-3,5- dicarboxylates from aldehydes and fluorinated β-oxo esters in the presence of ionic liquid-K2CO3 as catalytic system

An efficient procedure has been developed for the synthesis of 4-substituted 2,6-bis(fluoroalkyl)-2,6-dihydroxytetrahydro-2H-pyran-3,5- dicarboxylates by reactions of aldehydes with fluorine-containing β-oxo esters in heterogeneous catalytic system 1-buty