873957-41-6Relevant articles and documents
Synthesis and anti-HCV activity of 1-(1′,3′-O-anhydro-3′-C-methyl-β-d-psicofuranosyl)uracil
Komsta, Zofia,Mayes, Benjamin,Moussa, Adel,Shelbourne, Montserrat,Stewart, Alistair,Tyrrell, Andrew J.,Wallis, Laura L.,Weymouth-Wilson, Alexander C.,Yurek-George, Alexander
, p. 6216 - 6219 (2015/01/09)
Synthesis of a novel 1′,2′-oxetane-uridine bearing a 2′-C-methyl substituent, [1-(1′,3′-O-anhydro-3′-C-methyl-β-d-psicofuranosyl)uracil], is described. Key to its construction was the use of 6-O-(p-toluoyl)-1,2:3,4-di-O-isopropylidene-3-C-methyl-d-psicofu
PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS
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, (2008/12/07)
The present invention includes methods of treating or preventing cancer by administering an effective amount of 6-substituted pyrimidine derivatives of the Formula I to a subject need thereof:
ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA
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Page/Page column 46; 48-49, (2008/06/13)
The present invention includes methods of treating or preventing malaria by administering an anti-malarial effective amount of 6-substituted uridine derivatives to a subject need thereof. The invention also includes new 6-substituted uridine derivatives for use as therapeutics, in particular to treat malaria.
Facile preparation of the oxetane-nucleosides
Bogucka, Malgorzata,Naus, Petr,Pathmasiri, Wimal,Barman, Jharna,Chattopadhyaya, Jyoti
, p. 4362 - 4372 (2007/10/03)
Efficient and practical large scale synthesis of suitably protected 1′, 2′-oxetane locked purine and pyrimidine nucleosides for incorporation in oligo-DNA or -RNA by solid-phase synthesis is reported. A high regio and stereoselectivity with preferential f