34506-51-9Relevant academic research and scientific papers
Preparation of Polyfunctional Allenic Alcohols by the Regioselective Addition of Functionalized Propargylic Chromium(III) Organometallics to Carbonyl Compounds
Belyk, Kevin,Rozema, Michael J.,Knochel, Paul
, p. 4070 - 4074 (2007/10/02)
The reaction of propargylic halides 1 (X = Cl, Br) with an aldehyde or ketone (0.67 equiv) in the presence of CrCl2 (2.0 equiv) and LiI (2 equiv, necessary if X = Cl) affords allenic alcohols 3 with excellent regioselectivities (3-6percent of the regioiso
