34551-63-8

Basic information

• Product Name: (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone
• Synonyms: (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone
• CAS NO: 34551-63-8
• Molecular Weight: 314.341
• Mol File: 34551-63-8.mol

Chemical Properties

• CAS DataBase Reference: (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone(34551-63-8)
• EPA Substance Registry System: (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone(34551-63-8)

Safety Data

• Hazardous Substances Data: 34551-63-8(Hazardous Substances Data)

Upstream product

• 123-54-6 acetylacetone 
• 552-89-6 2-nitro-benzaldehyde 
• 60-35-5 acetamide 
• 506-87-6 ammonium carbonate 
• 105-45-3 acetoacetic acid methyl ester 
• 27669-22-3 3-(2-nitrobenzylidene)pentane-2,4-dione 
• 1118-66-7 4-amino-3-penten-2-one 

Downstream Products

• 34551-62-7 3,5-diacetyl-2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine 
• 94771-72-9 1-Acetyl-2,4,5-trimethyl-3,6-diazaphenanthren 
• 94771-70-7 3,5-Diacetyl-2,6-dimethyl-4-(2-nitrosophenyl)-pyridin 
• 94771-71-8 bis-[2-(3,5-diacetyl-2,6-dimethyl-[4]pyridyl)-phenyl]-diazene-N,N'-dioxide 
• 94398-03-5 3,5-Diacetyl-2,6-dimethyl-4-(2-nitrophenyl)-pyridin 

Relevant articles and documents

Solvent-free efficient one-pot synthesis of Biginelli and Hantzsch compounds catalyzed by potassium phthalimide as a green and reusable organocatalyst

The usage of potassium phthalimide (PPI) for the simple and green one-step multicomponent synthesis of Hantzsch 1,4-dihydropyridines, polyhydroquinolines, 3,4-dihydropyrimidin-2(1H)-ones/thiones, and octahydroquinazolinones under solventless conditions at 120°C is reported. The method is operationally simple, environmentally benign, and has relatively high yields. The other merits of this method include efficient, clean, green, and catalyst reusability.

Ultrasound-mediated, uranyl nitrate hexahydrate-catalyzed synthesis of 1,4-dihydropyridines under mild conditions

Abstract Synthesis of 1,4-dihydropyridines by three-component condensation reaction of aldehyde, 1,3-dicarbonyl compounds, and ammonium acetate have been found to be efficiently catalyzed by uranyl nitrate hexahydrate [UO2(NO3)2 ·6H2O] at room temperature under ultrasound irradiation. This novel synthetic method offers the advantages of high yields, short reaction times, simplicity, and easy workup compared to the conventional methods reported in the literature.

Synthesis and 3D-QSAR study of 1,4-dihydropyridine derivatives as MDR cancer reverters

A series of symmetrical and unsymmetrical 1,4-dihydropyridines were synthesized by a rapid, single pot microwave irradiation (MWI) based protocol along with conventional approach and characterized by NMR, IR and mass spectroscopic techniques. The compound

Ionic liquid [EMIM]OAc under ultrasonic irradiation towards synthesis of 1,4-DHP's

The ionic liquid 1-ethyl-3-methylimidazole acetate ([EMIM]OAc) was found to be a mild and effective catalyst for the efficient, one-pot, three-component synthesis of 1,4-dihydropyridines from arylalde-hydes, ethylacetoacetate/ acetylacetone and ammonium acetate at room temperature under sonication. The developed method has many advantages, including devoid of harmful catalysts, reacting at room temperature, higher yields in a simple methodology or operational convenience.

Etidronic acid catalyzed synthesis of 1,4-dihydropyridines

One pot, three components cyclaconctensation reaction of various arylaldehydes. ethyl acetoacetate/acetyl acetone and ammonium acetate with etidronic acid as catalyst afforded the corresponding 1,4 -dihydropyridines in better yields under solvent free conditions.

Etidronic acid catalyzed synthesis of 1,4-dihydropyridines

One pot, three components cyclocondensation reaction of various arylaldehydes, ethyl acetoacetate/acetyl acetone and ammonium acetate with etidronic acid as catalyst afforded the corresponding 1,4-dihydropyridines in better yields under solvent free conditions.

Candida antarctica lipase B-catalyzed the unprecedented three-component Hantzsch-type reaction of aldehyde with acetamide and 1,3-dicarbonyl compounds in non-aqueous solvent

A direct approach to 1,4-dihydropyridines by lipase-catalyzed unprecedented three-component Hantzschtype reaction of aldehyde with 1,3-dicarbonyl compounds and acetamide in non-aqueous solvent has been developed. Some control experiments have been perform

Synthesis of Hantzsch 1,4-dihydropyridines under solvent-free condition using Zn[(L)proline]2 as Lewis acid catalyst

The present short communication describes a Lewis acid (Zn[(L)proline] 2) catalysed one pot synthesis of Hantzsch 1,4-dihydropyridine (DHP) derivatives under solvent-free condition by conventional heating and microwave irradiation. The Lewis acid catalyst Zn[(L)proline]2 used in this reaction afford moderate to good yield. The catalyst is reusable upto five cycles without appreciable loss of its catalytic activity.

A novel TMSI-mediated synthesis of Hantzsch 1,4-dihydropyridines at ambient temperature

The synthesis of various substituted Hantzsch 1,4-dihydropyridines has been achieved using the classical Hantzsch procedure and modified Hantzsch conditions for the first time at room temperature in the presence of iodotrimethylsilane (TMSI) generated in situ in CH3CN, in excellent yields.