(2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone

Base Information

• Chemical Name: (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone
• CAS No.: 34551-63-8
• Molecular Formula: C₁₇H₁₈N₂O₄
• Molecular Weight: 314.341
• Mol file: 34551-63-8.mol

Synonyms:(2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone

Chemical Property of (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone

There total 10 articles about (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

acetylacetone (123-54-6,81235-32-7) + 2-nitro-benzaldehyde (552-89-6) → (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone (34551-63-8)

Guidance literature:

With ammonium acetate; 1-ethyl-3-methylimidazolium acetate; In ethanol; at 20 ℃; for 0.583333h; Sonication;

DOI:10.1002/jccs.201190041

Reference yield: 85.0%

acetamide (60-35-5) + acetylacetone (123-54-6,81235-32-7) + 2-nitro-benzaldehyde (552-89-6) → (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone (34551-63-8)

Guidance literature:

With Candida antarctica lipase B immobilized on acrylic resin; In tert-butyl methyl ether; at 50 ℃; for 72h;

DOI:10.1016/j.tet.2011.01.045

Reference yield: 73.0%

acetoacetic acid methyl ester (105-45-3) + 2-nitro-benzaldehyde (552-89-6) → (2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)diethanone (34551-63-8)

Guidance literature:

With chloro-trimethyl-silane; ammonium acetate; sodium iodide; In acetonitrile; at 20 ℃; for 8h;

DOI:10.1016/S0040-4039(03)00813-X

upstream raw materials:

4-amino-3-penten-2-one

3-(2-nitrobenzylidene)pentane-2,4-dione

acetylacetone

2-nitro-benzaldehyde

Downstream raw materials:

1-Acetyl-2,4,5-trimethyl-3,6-diazaphenanthren

3,5-Diacetyl-2,6-dimethyl-4-(2-nitrosophenyl)-pyridin

bis-[2-(3,5-diacetyl-2,6-dimethyl-[4]pyridyl)-phenyl]-diazene-N,N'-dioxide

3,5-diacetyl-2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine