345633-49-0

Upstream product

• 86560-40-9 2-(3-oxocyclohexyl)acetonitrile 
• 345633-53-6 [2-[7,12]-dioxa-spiro[5,6]dodec-2-yl]-ethylamine 
• 345633-51-4 [[7,12]-dioxa-spiro[5,6]dodec-2-yl]-acetonitrile 
• 930-68-7 cyclohexenone 
• 345633-59-2 [2-[7,12-dioxa-spiro[5,6]dodec-2-yl]-ethyl]-[2-methoxy-but-3-enyl]-amine 

Relevant academic research and scientific papers

Tandem cationic aza-cope rearrangement-Mannich cyclization approach to the core structure of FR901483 via a Bridgehead iminium ion.

[reaction in text] An approach to the potent immunosuppressant FR901483 is described. This route utilizes a tandem cationic aza-Cope rearrangement-Mannich cyclization to generate the core structure of this compound. In addition, this is the first demonstr