34575-25-2Relevant academic research and scientific papers
New Synthesis of Optically Active 5-Isoxazolidinones and β-Amino Acids
Luisi, Renzo,Capriati, Vito,Florio, Saverio,Vista, Teresa
, p. 9861 - 9864 (2007/10/03)
A new simple and stereoselective synthesis of 5-isoxazolidinones based on the reaction of lithiated 2-isopropyl-2-oxazolines with nitrones is described. A chiral version of such a methodology allows the preparation of highly enantioenriched 5-isoxazolidinones which are useful precursors for the synthesis of β-amino acids.
Alkyl Nitrate Nitration of Active Methylene Compounds. Nitration of 2-Substituted 2-Oxazolines
Feuer, Henry,Bevinakatti, Hanamanthsa S.,Luo, Xuan-Gan
, p. 825 - 832 (2007/10/02)
2-Alkyl- and 2-aralkyl-2-oxazolines are readily converted to the corresponding α-nitroalkyl- and α-nitroaralkyl-2-oxazolines an treatment with an alkali metal amide such as potassium or sodium amide in liquid ammonia or with lithium diisopropylamide (LDA)
SYNTHESIS OF ISOTHIOCYANATES FROM NON-AROMATIC NITROGEN-CONTAINING HETEROCYCLES
Gonda, Jozef,Kristian, Pavol,Mikler, Lubomir
, p. 112 - 117 (2007/10/02)
Investigation of the reaction of thiophosgene with Δ2-oxazolines I, Δ3-thiazolines II, 4H-benzothiazines III, 2-methoxypentahydro-Δ1-azepine IV, theophylline and caffeine showed that only compounds I and IV reacted to give 2-acyloxyethyl isothiocyanates and methyl 6-isothiocyanatohexanoate.The structure of these products was corroborated by IR, 1H NMR, 13C NMR and mass spectral methods.The suitability of the above-mentioned compounds to react is discussed.
Allenes. Part 44. Formation of Oxazolines and Benzoxazoles from Allenic nitriles and amides and from Phenylpropynenitrile.
Fomum, Z. Tanee,Nkengfack, A. Ephrem,Mpango, George W. P.,Landor, Stephen R.,Landor, Phyllis D.
, p. 901 - 924 (2007/10/02)
Michael addition of ethanolamines and 2-aminophenol to allenic nitriles, allenic amides and phenylpropynenitrile gives enaminic nitriles and amides which at 290 deg - 320 deg yield oxazolines and benzoxazoles.
