3458-98-8

Basic information

• Product Name: 3-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
• Synonyms: 3-(2-aminoethyl)-phenohydrochloride;3-hydroxy-benzeneethanaminhydrochloride;M-TYRAMINE HYDROCHLORIDE;3-HYDROXYPHENETHYLAMINE HYDROCHLORIDE (M -TYRAMINE HCL) DOP;2-(3-Hydroxyphenyl)ethanamineHCl;3-(2-AMino-ethyl)-phenol HCl;3-Hydroxyphenethylamine, HCl
• CAS NO: 3458-98-8
• Molecular Formula: C₈H₁₁NO*ClH
• Molecular Weight: 173.64
• EINECS: 222-396-6
• Mol File: 3458-98-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 162 °C
• Boiling Point: 275.5 °C at 760 mmHg
• Flash Point: 120.4 °C
• Appearance: off-white to tan/solid
• Vapor Pressure: 0.00303mmHg at 25°C
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: H2O: ≥10 mg/mL
• CAS DataBase Reference: 3-HYDROXYPHENETHYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-HYDROXYPHENETHYLAMINE HYDROCHLORIDE(3458-98-8)
• EPA Substance Registry System: 3-HYDROXYPHENETHYLAMINE HYDROCHLORIDE(3458-98-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: SJ5975000
• Hazardous Substances Data: 3458-98-8(Hazardous Substances Data)

Usage

Uses

m-Tyramine Hydrochloride affects the firing pattern of Heobania vermiculata. Potential organ or tumor imaging agent.

InChI:InChI=1/C8H11NO.ClH/c9-5-4-7-2-1-3-8(10)6-7;/h1-3,6,10H,4-5,9H2;1H

Upstream product

• 536-21-0 norfenefrine 
• 2039-67-0 2-(3-methoxyphenyl)-1-ethanamine 
• 19924-43-7 3-methoxyphenylacetonitrile 
• 20967-96-8 2-(3-benzyloxyphenyl)acetonitrile 

Downstream Products

• 14446-24-3 6-hydroxy-1,2,3,4-tetrahydroisoquinoline 
• 32999-37-4 1,2,3,4-tetrahydroisoquinoline-8-ol 
• 42061-75-6 2-(5-Hydroxy-2-iodphenyl)aethylamin 
• 171515-38-1 N-(Trifluoroacetyl)-3-hydroxyphenylethylamine 
• 193682-78-9 1-Benzyloxymethyl-6-hydroxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 129150-68-1 N-(t-butoxycarbonyl)-2-(3-hydroxyphenyl)-ethylamine 
• 194855-05-5 1-hydroxy-3-(2-carbobenzyloxyamino)ethyl benzene 
• 63905-73-7 6-hydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 935252-61-2 3-[2-(5-chlorothieno[2,3-d]-pyrimidin-4-ylamino)ethyl]phenol 
• 1262287-86-4 3-(2-{[6-chloro-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-yl]amino}ethyl)phenol 
• 91523-50-1 rac-6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid 
• 1400661-75-7 5-[2-(3-hydroxy-phenyl)-ethyl-carbamoyl]-3-methyl-thiophene-2-carboxylic acid methyl ester 
• 1415657-84-9 3-(2-(2-((3-hydroxyphenethyl)amino)-2-oxoethoxy)phenyl)-N-(2-(2-(3-iodophenyl)-N-methylacetamido)ethyl)-N-methylpropanamide 

Relevant articles and documents

SUBSTITUTED HYDROXYPHENYLAMINE COMPOUNDS

The present invention relates to new substituted hydroxyphenylamine based modulators of hormone and/or pigment levels, pharmaceutical compositions thereof, and methods of use thereof. Formula (I).

Regioselective synthesis of 6-fluorodopamine, 6-fluoro-m-tyramine and 4-fluoro-m-tyramine using elemental fluorine, oxygen difluoride and acetyl hypofluorite

6-Fluorodopamine was regioselectively synthesized in good yields from N-(trifluoroacetyl)-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)phenylethylamine (6) via a fluorodestannylation reaction using F2, OF2 or CH3COOF followed by acid hydrolysis.Similarly, 6-fluoro-m-tyramine (14) and 4-fluoro-m-tyramine (20) were prepared from their corresponding trimethylstannyl derivatives.All precursors and products were fully characterized by multinuclear NMR spectroscopy and high resolution mass spectrometry. - Keywords: Dopamine neurotransmission; Norepinephrine synthesis; Dopamine agonist; 6-fluorodopamine; Fluorodestannylation