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2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester is a chemical compound that serves as a versatile linker for bioconjugation and a crosslinking reagent in biochemistry and molecular biology. Derived from 2,6-diaminohexanoic acid, 2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester has a molecular weight of 649.13 g/mol and is recognized for its capability to form stable amide bonds. It is instrumental in the synthesis of peptides and proteins and as a chemical modification agent for the functionalization of biomolecules and surfaces, making it an essential tool in scientific research.

345898-28-4

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345898-28-4 Usage

Uses

Used in Bioconjugation:
2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester is used as a linker in bioconjugation for the attachment of various biomolecules, such as proteins, nucleic acids, and other ligands, to create conjugates with specific functions and improved stability.
Used in Crosslinking:
In the field of molecular biology, 2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester is used as a crosslinking reagent to connect different biomolecules, facilitating the study of molecular interactions and the construction of bioconjugates with enhanced properties.
Used in Peptide and Protein Synthesis:
2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester is utilized in the synthesis of peptides and proteins, enabling the formation of stable amide bonds and contributing to the development of novel bioactive molecules.
Used in Chemical Modification of Biomolecules and Surfaces:
2,6,10,15-Tetraazahexadecanedioic acid,
6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl)
1-(2,2,2-trichloroethyl) ester serves as a chemical modification agent, allowing for the functionalization of biomolecules and surfaces to enhance their properties or introduce new functionalities, which is crucial in various scientific research applications.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester may be employed in the design and synthesis of drug candidates, potentially improving drug delivery, targeting, and efficacy.
Used in Diagnostics and Imaging:
In diagnostic applications, 2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester can be used to modify imaging agents or develop new contrast agents for enhanced imaging capabilities in medical diagnostics.
Used in Material Science:
2,6,10,15-Tetraazahexadecanedioic acid, 6,10-bis[(phenylmethoxy)carbonyl]-, 16-(1,1-dimethylethyl) 1-(2,2,2-trichloroethyl) ester can be applied in the development of biocompatible materials and coatings, contributing to advances in areas such as tissue engineering and biomedicine.

Check Digit Verification of cas no

The CAS Registry Mumber 345898-28-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,5,8,9 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 345898-28:
(8*3)+(7*4)+(6*5)+(5*8)+(4*9)+(3*8)+(2*2)+(1*8)=194
194 % 10 = 4
So 345898-28-4 is a valid CAS Registry Number.

345898-28-4Relevant academic research and scientific papers

Total synthesis of the novel spider toxin NPTX-594 from Nephila madagascariencis

Wakamiya, Tateaki,Yamamoto, Akinori,Kawaguchi, Keita,Kinoshita, Tomohiko,Yamaguchi, Yoshihiro,Itagaki, Yasuhiro,Naoki, Hideo,Nakajima, Terumi

, p. 1743 - 1749 (2007/10/03)

A novel spider toxin, NPTX-594, comprised of four constituents: i.e., 2,4-dihydroxyphenylacetic acid (Dhpa), asparagine, 4,8-diaza-1,12-dodecanediamine (Dada), and lysine, was chemically synthesized. The synthetic compound was completely identical with the natural product as regards 1H NMR and mass spectra. The structure of NPTX-594 was thus determined synthetically to be N12-(Dhpa-Asn)-N1-Lys-Dada, as proposed by spectrometric elucidation.

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