346433-44-1Relevant academic research and scientific papers
A mild anionic method for generating o-quinone methides: Facile preparations of ortho-functionalized phenols
Jones,Van De Water,Lindsey,Hoarau,Ung,Pettus
, p. 3435 - 3441 (2001)
A low-temperature method for generating o-quinone methides is described which permits facile introduction of assorted R substituents onto the aryl ring system at low temperature. The method is useful for the efficient preparation of ortho-ring-alkylated phenols.
Organocatalytic methods for chemoselective O-tert-butoxycarbonylation of phenols and their regeneration from the O-t-Boc derivatives
Chankeshwara, Sunay V.,Chebolu, Rajesh,Chakraborti, Asit K.
supporting information; scheme or table, p. 8615 - 8618 (2009/04/11)
(Chemical Equation Presented) Carbon tetrabromide (CBr4) catalyzes O-tert-butoxycarbonylation of functionalized phenols without any side reactions (bromination, addition of CBr3 to a double bond, and formation of symmetrical diaryl carbonates, cyclic carbonates, or carbonic-carbonic anhydrides). The parent phenols are regenerated from the O-t-Boc derivatives by the catalyst system CBr4-PPh3 without affecting other protecting groups (aryl alkyl ether, alkyl ester, and thioacetal) or competitive side reaction such as bromination, nitrene (from NO2) and α,α-dibromoolefine (with CHO/COMe) formation, and transesterification (with CO2Me/Et) taking place.
Triphenylphosphine as a novel organocatalyst for chemoselective O-tert-butoxycarbonylation of phenols
Chebolu, Rajesh,Chankeshwara, Sunay V.,Chakraborti, Asit K.
, p. 1448 - 1454 (2008/12/21)
A novel organocatalytic procedure for the chemoselective O-tert-butoxycarbonylation of phenols under neutral and neat conditions is described. Georg Thieme Verlag Stuttgart.
