346687-19-2

Upstream product

• 129951-46-8 4,5-difluoro-2-nitrobenzoyl chloride 
• 20372-63-8 4,5-difluoro-2-nitrobenzoic acid 
• 455-86-7 3,4-Difluorobenzoic acid 

Downstream Products

• 383875-96-5 6,7-difluoro-2-phenyl-1-prenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester 
• 346687-26-1 6,7-difluoro-2-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 
• 383875-98-7 6,7-difluoro-2-phenyl-1-prenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 
• 346687-24-9 ethyl 6,7-difluoro-2-phenyl-4-oxoquinoline-3-carboxylate 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of 2-substituted 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

A series of 2-substituted 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for antibacterial activity. The 6-fluoro-2-methyl-1-prenyl-1,4-dihydro-7-(3,5-dimethylpiperazinyl)-4-oxo-3-quinolinecarboxylic acid (14f) exhibited

Synthesis of 4-Hydroxyquinolin-2(1H)-one analogues and 2-substituted quinolone derivatives

A versatile synthetic method for preparing 4-hydroxyquinolone and 2-substituted quinolone compounds from simple benzoic acid derivatives was demonstrated. The synthetic strategies involve the use of well known ethyl acetoacetate synthesis, malonic ester s