347-82-0 Usage
Uses
Used in Organic Synthesis:
Phenol, 4-fluoro-, 4-nitrobenzoate is utilized as a key intermediate in the synthesis of various organic compounds. Its presence in the molecule allows for a range of chemical reactions, making it a valuable building block in the creation of new molecules.
Used in Pharmaceutical Production:
Phenol, 4-fluoro-, 4-nitrobenzoate is employed as a precursor in the development of pharmaceuticals. Its unique structure contributes to the design of new drugs, particularly those targeting diseases such as cancer and inflammation. Phenol, 4-fluoro-, 4-nitrobenzoate's versatility in chemical reactions enables the creation of potential therapeutic agents.
Used in Dye Production:
In the dye industry, Phenol, 4-fluoro-, 4-nitrobenzoate is used as a starting material for the synthesis of various dyes. The presence of the phenol, fluorine, and nitro groups in the molecule allows for the creation of dyes with specific color properties and stability.
Used in Agrochemical Production:
Phenol, 4-fluoro-, 4-nitrobenzoate is also used in the agrochemical industry, where it serves as a building block for the development of new agrochemicals. Its chemical properties make it suitable for the synthesis of compounds that can be used in crop protection and other agricultural applications.
Used in Cancer Treatment Research:
Phenol, 4-fluoro-, 4-nitrobenzoate has been studied for its potential use in the treatment of cancer. Its biological activities suggest that it may have therapeutic potential, and ongoing research is focused on understanding its mechanisms of action and potential applications in cancer therapy.
Used in Inflammation Treatment Research:
Similar to its potential use in cancer treatment, Phenol, 4-fluoro-, 4-nitrobenzoate is also being investigated for its potential role in the treatment of inflammation. Its unique structure and functional groups may contribute to anti-inflammatory effects, making it a subject of interest for researchers in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 347-82-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 347-82:
(5*3)+(4*4)+(3*7)+(2*8)+(1*2)=70
70 % 10 = 0
So 347-82-0 is a valid CAS Registry Number.
347-82-0Relevant academic research and scientific papers
Decarboxylative Hydroxylation of Benzoic Acids
Ritter, Tobias,Su, Wanqi,Xu, Peng
supporting information, p. 24012 - 24017 (2021/10/06)
Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 °C via photoinduced ligand-to-metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation. The aromatic decarboxylative hydroxylation is synthetically promising due to its mild conditions, broad substrate scope, and late-stage applications.
Preparation of 4-fluorophenol and 4-fluorobenzoic acid by the Baeyer-Villiger reaction
Conte, L.,Napoli, M.,Gambaretto, J. P.,Guerrato, A.,Carlini, F. M.
, p. 41 - 46 (2007/10/02)
The possibility of preparing 4-fluorophenol or 4-fluorobenzoic acid via the Baeyer-Villiger reaction starting from unsymmetrical fluoroaryl ketones is disscussed.Several unsymmetrical 4-fluorobenzophenones having different substituents in the fluorine-free aryl group were prepared and converted to esters by treatment with peracetic acid.The electrophilicity of the substituents influenced the molecular structure of the ester formed as a result of a carbon-to-oxygen migration, and hence 4-fluorophenol or 4-fluorobenzoic acid formation.Electron-withdrawing substituents favoured the formation of 4-fluorophenol in good yields, while electron-donating substituents formed 4-fluorobenzoic acid preferentially.
