34701-14-9

Basic information

• Product Name: 4-NITROINDAN
• Synonyms: 4-NITROINDAN;2,3-Dihydro-4-nitro-1H-indene;4-nitro-2,3-dihydro-1H-indene;4-nitroindane;1H-Indene, 2,3-dihydro-4-nitro-;4-Nitroindan 99%
• CAS NO: 34701-14-9
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.17
• EINECS: 252-159-2
• Product Categories: Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
• Mol File: 34701-14-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 41-43 °C(lit.)
• Boiling Point: 105-107 °C6 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.2021 (rough estimate)
• Vapor Pressure: 0.00941mmHg at 25°C
• Refractive Index: 1.5460 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-NITROINDAN(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NITROINDAN(34701-14-9)
• EPA Substance Registry System: 4-NITROINDAN(34701-14-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 34701-14-9(Hazardous Substances Data)

Usage

General Description

4-NITROINDAN is a chemical compound with the molecular formula C9H7NO2. It is a nitro-substituted indane derivative, which means it is composed of a benzene ring fused to a cyclopentane ring with a nitro group attached to the benzene ring. It is a yellow crystalline solid that is sparingly soluble in water but soluble in organic solvents. 4-NITROINDAN is commonly used as a building block in the synthesis of various organic compounds, such as pharmaceuticals, agrochemicals, and dyes. It is also used as an intermediate in the production of perfumes and flavorings. Additionally, it is known to exhibit potential therapeutic properties in the treatment of certain diseases, making it an important chemical in the field of medicinal chemistry.

InChI:InChI=1/C9H9NO2/c11-10(12)9-6-2-4-7-3-1-5-8(7)9/h2,4,6H,1,3,5H2

Upstream product

• 496-11-7 INDANE 

Downstream Products

• 32202-61-2 4-aminoindan 
• 24623-25-4 4-nitro-2,3-dihydro-1H-inden-1-one 
• 603-11-2 3-nitrophthalic acid 
• 943724-56-9 C₂₅H₁₉N₃O₂S 
• 943724-58-1 C₂₃H₁₇N₃OS 
• 51135-91-2 4-amino-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

NLRP3 INHIBITORS

The present application relates to compounds with NLRP3inhibitory activity and to associated salts, solvates, prodrugs and pharmaceutical compositions. The present application further relates to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3inhibition.

NOVEL COMPOUNDS

The present invention relates to substituted 5-membered nitrogen containing heteroaryl compounds, such as sulfonyl triazoles, where the heteroaryl ring is further substituted, optionally via a linking group such as -NH-, with a cyclic group which in turn is substituted at the α-position. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.

2,4-DI(AMINOPHENYL) PYRIMIDINES AS PLK INHIBITORS

The invention relates to compounds of general formula (1), wherein A, W, X, Y, Z, Ra, Rb, Rc, R1, and R3 are defined as indicated in claim 1. Said compounds are used for the treatment of diseases characterized by excessive or anomalous cell proliferation. Also disclosed is the use of the inventive compounds for producing a medicament having said properties.