34737-83-2

Basic information

• Product Name: 1-Methyl-4-piperidinol hydrochloride
• Synonyms: 1-METHYL-4-PIPERIDONE HCL;1-METHYL-4-PIPERIDONE HYDROCHLORIDE;1-methyl-4-piperidinol hydrochloride;N-Methyl-4-piperideone hydrochloride;1-Methylpiperidin-4-one hydrochloride
• CAS NO: 34737-83-2
• Molecular Formula: C₆H₁₁NO*ClH
• Molecular Weight: 149.62
• Product Categories: Piperidines, Piperidones, Piperazines
• Mol File: 34737-83-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 95 °C
• Boiling Point: 236.8 °C at 760 mmHg
• Flash Point: 97 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-Methyl-4-piperidinol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-4-piperidinol hydrochloride(34737-83-2)
• EPA Substance Registry System: 1-Methyl-4-piperidinol hydrochloride(34737-83-2)

Safety Data

• Hazardous Substances Data: 34737-83-2(Hazardous Substances Data)

Usage

General Description

1-Methyl-4-piperidinol hydrochloride is a chemical compound with the molecular formula C6H13NO?HCl. It is a derivative of piperidine and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-Methyl-4-piperidinol hydrochloride is a solid, white crystalline powder that is soluble in water and methanol. It has a molecular weight of 159.63 g/mol. 1-Methyl-4-piperidinol hydrochloride is known for its mild, pleasant odor and is commonly used in the production of antihistamines and muscle relaxants. It is also used as a building block in the synthesis of other organic compounds. Overall, 1-Methyl-4-piperidinol hydrochloride is an important intermediate in the pharmaceutical and agrochemical industries.

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 13221-89-1 1-methyl-4-oxo-piperidine-3-carboxylic acid methyl ester 
• 3518-85-2 methylimine-N,N-dipropionate methyl ester 
• 73390-09-7 4,4-Dihydroxy-1-methylpiperidinium-chlorid 

Downstream Products

• 20734-30-9 4-cyano-4-hydroxy-1-methylpiperidine 
• 106-52-5 N-methyl-4-hydroxypiperidine 
• 28286-05-7 8-Methyl-1,4-dioxa-8-azoniaspiro<4.5>decan 
• 41838-46-4 4-Amino-1-methylpiperidine 
• 524-81-2 mebhydrolin 

Relevant articles and documents

Preparation method of mebhydrolin napadisylate

The invention belongs to the field of drug synthesis and provides a preparation method of mebhydrolin napadisylate. The preparation method is characterized by including the steps of firstly, subjecting methyl imine-N,N-methyl dipropionate and sodium methylate to heating under the effect of an organic solvent to achieve loop closing, and using hydrochloric acid to performing heating decarboxylationto obtain N-methyl-4-piperidone hydrochloride; subjecting phenylhydrazine and benzyl chloride to condensation under an alkaline condition to obtain benzyl phenylhydrazine; thirdly, mixing the N-methyl-4-piperidone hydrochloride solution and the benzyl phenylhydrazine, heating to generate mebhydrolin hydrochloride, adding disodium 1,5-naphthalenedisulfonate to obtain the mebhydrolin napadisylate.The preparation method is high in yield, mild in reaction conditions, convenient in intermediate purification and capable of satisfying the requirements of industrial production.

Isonitrile intermediates for the preparation of tri-substituted imidazole compounds with multiple therapeutic properties

The invention relates to a novel group of isonitrile compounds and a process for their preparation, useful in the preparation of tri-substituted imadazoles having multiple therapeutic properties.

Formamide intermediates for the preparation of tri-substituted imidazole compounds with multiple therapeutic properties

The invention relates to a novel group of formamide compounds and a process for their preparation, useful in the preparation of tri-substituted imadazoles having multiple therapeutic properties.