34765-54-3Relevant academic research and scientific papers
Traceless solid-phase synthesis of 2-amino-5-alkylidene-thiazol-4-ones
Pulici, Maurizio,Quartieri, Francesca
, p. 2387 - 2391 (2005)
2-Amino-5-alkylidene-thiazol-4-ones bearing two diversity points are prepared by a solid-phase strategy exploiting rhodanine as the starting material. Rhodanine is first loaded on bromo-Wang resin, subjected to Knovenagel condensation with aldehydes, and cleaved off the resin in a traceless manner by means of an amine.
SYNTHESIS OF 2-SUBSTITUTED 5-ARYLIDENETHIAZOLIN-4-ONES FROM α,β-UNSATURATED ACYL ISOTHIOCYANATES
Kutschy, Peter,Dzurilla, Milan,Kristian, Pavol,Kutschyova, Kvetoslava
, p. 436 - 445 (2007/10/02)
α,β-Unsaturated acyl isothiocyanates react with N-methylaniline to give thioureas which, when treated with bromine in chloroform, afford benzothiazoline derivatives.Under the same reaction conditions primary amines, diethylamine,piperidine and morpholine
