34784-07-1

Basic information

• Product Name: 8-Chloroisoquinoline
• Synonyms: 8-Chloroisoquinoline 95%;8-Chloroisoquinoline;8-Chloro-2-azanaphthalene;8-Chloroisoquinoline95%;Isoquinoline, 8-chloro-
• CAS NO: 34784-07-1
• Molecular Formula: C₉H₆ClN
• Molecular Weight: 163.6
• EINECS: -0
• Product Categories: blocks;Heterocycles;Quinolines;Heterocyclic Series;Quinoline&Isoquinoline;Aromatics;Miscellaneous Reagents
• Mol File: 34784-07-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 55.5-56.5 °C
• Boiling Point: 289.463 °C at 760 mmHg
• Flash Point: 156.429 °C
• Appearance: /
• Density: 1.27 g/cm³
• Vapor Pressure: 0.00382mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.63±0.23(Predicted)
• CAS DataBase Reference: 8-Chloroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Chloroisoquinoline(34784-07-1)
• EPA Substance Registry System: 8-Chloroisoquinoline(34784-07-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 34784-07-1(Hazardous Substances Data)

Usage

Uses

Substituted isoquinoline.

InChI:InChI=1/C9H6ClN/c10-9-3-1-2-7-4-5-11-6-8(7)9/h1-6H

Upstream product

• 956003-79-5 8-chloro-5-bromo-isoquinoline 
• 34784-04-8 5-bromoisoquinoline 
• 119-65-3 isoquinoline 
• 587-04-2 m-Chlorobenzaldehyde 
• 22483-09-6 2,2-dimethoxyethylamine 

Downstream Products

• 156901-43-8 8-chloro-5-nitroisoquinoline 
• 3482-14-2 isoquinolin-8-ol 
• 119-65-3 isoquinoline 
• 1215767-86-4 4-bromo-8-chloro-isoquinoline 
• 848841-64-5 1,8-dichloro-isoquinoline 
• 76304-19-3 8-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline 
• 69381-55-1 8-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 863290-56-6 8-chloro-1-(3,4-dimethoxy-benzyl)-isoquinoline 
• 863290-48-6 2-benzoyl-8-chloro-1-cyano-1,2-dihydroisoquinoline 
• 76304-17-1 8-(4-methoxyphenyl)isoquinoline 
• 70125-67-6 8-phenylisoquinoline 
• 70810-27-4 8-chloroisoquinoline N-oxide 

Relevant articles and documents

Regioexhaustive Functionalization of the Carbocyclic Core of Isoquinoline: Concise Synthesis of Oxoaporphine Core and Ellipticine

A general and versatile strategy has been developed for the functionalization of the carbocyclic core of the isoquinoline. This regioexhaustive approach employs electrophilic halogenation as a toolbox methodology and delivers highly decorated intermediates that can be further elaborated toward medicinally relevant building blocks or natural products.