347885-02-3Relevant academic research and scientific papers
Cross-dehydrogenative coupling between enamino esters and ketones: Synthesis of tetrasubstituted pyrroles
Zhao, Miao,Wang, Fen,Li, Xingwei
, p. 1412 - 1415 (2012/05/04)
Tetrasubstituted pyrroles have been synthesized via the cross-dehydrogenative coupling between enamino esters and acetone. Silver carbonate proved to be an effective oxidant, and no transition metal catalyst is necessary.
Indium-catalyzed synthesis of furans and pyrroles via cyclization of α-propargyl-β-keto esters
Tsuji, Hayato,Yamagata, Ken-Ichi,Ueda, Yasuyuki,Nakamura, Eiichi
supporting information; experimental part, p. 1015 - 1017 (2011/06/17)
In(OTf)3 or In(NTf2)3 effectively catalyze the cyclo-isomerization reaction of -propargyl - keto esters and their imine analogues to afford trisubstituted furans and pyrroles, respectively. Both terminal and internal alkyn
Synthesis of highly substituted pyrroles via a multimetal-catalyzed rearrangement-condensation-cyclization domino approach
Binder, Joerg T.,Kirsch, Stefan F.
, p. 2151 - 2153 (2007/10/03)
In a convenient one-pot process, easily accessed propargyl vinyl ethers and aromatic amines are effectively converted into tetra- and pentasubstituted 5-methylpyrroles which can further be transformed into 5-formylpyrroles via IBX-mediated oxidation. The
Cyclic AMP-specific phosphodiesterase inhibitors
-
, (2008/06/13)
Pyrrole compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as
