348136-10-7

Upstream product

• 108943-45-9 (R)-(+)-5-propyl-δ-valerolactone 
• 483287-64-5 (R,R)-(+)-N-(1-(1-naphthyl)ethyl)-5-hydroxyoctanamide 
• 698-76-0 6-propyl-tetrahydro-pyran-2-one 
• 98-88-4 benzoyl chloride 
• 149071-04-5 (R)-(-)-5-hydroxyoctanol 

Downstream Products

• 348136-12-9 (S)-(+)-5-fluorooctyl benzoate 

Relevant academic research and scientific papers

Optical resolution of 5-alkyl-δ-valerolactones and synthesis of optically active 5-fluoroalkanols

Optical resolutions of 5-alkyl-δ-valerolactones were carried out by derivatization to the diastereomeric amides, in which (R)-(+)-1-(1-naphthyl)ethylamine or (S)-(-)-1-phenylethylamine were used as resolving agents. Optically active 5-fluoroalkanols, useful intermediates for fluorinated ferroelectric liquid crystals, were derived from the resolved lactones in four steps without racemization.