34815-78-6

Basic information

• Product Name: 3-<3,5-bis(trifluoromethyl)phenyl>butan-2-ol
• CAS NO: 34815-78-6
• Molecular Weight: 286.217
• Mol File: 34815-78-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-<3,5-bis(trifluoromethyl)phenyl>butan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-<3,5-bis(trifluoromethyl)phenyl>butan-2-ol(34815-78-6)
• EPA Substance Registry System: 3-<3,5-bis(trifluoromethyl)phenyl>butan-2-ol(34815-78-6)

Safety Data

• Hazardous Substances Data: 34815-78-6(Hazardous Substances Data)

Upstream product

• 155619-05-9 2-<3,5-bis(trifluoromethyl)phenyl>propanal 
• 74-88-4 methyl iodide 
• 155619-04-8 2-<3,5-bis(trifluoromethyl)phenyl>propan-1-ol 
• 67570-38-1 α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanol 
• 66875-48-7 1-(prop-1-en-2-yl)-3,5-bis(trifluoromethyl)benzene 
• 328-70-1 3,6-bis(trifluoromethyl)bromobenzene 

Relevant articles and documents

Acetolysis of 2-Aryl-1-methylpropyl Systems: Mechanism of the Formation of the Retained Product without Neighbouring Group Participation

threo-2--1-(13C)methylpropyl p-bromobenzenesulphonate (threo-(13C)1-OBs) has been solvolyzed in acetic acid to give rise to the retained threo-1-OAc which contains a small amount of threo-(13C)1-OAc accompanying no 13C-scrambling.At 75percent conversion, the isomerized erythro-1-OBs has been obtained along with the unchanged threo-1-OBs.Also, the erythro-1-OTs has been found at 50percent conversion in the presence of NaOTs.These stereochemical results indicate strongly that the acetate with the retained configuration accompanying no 13C-scrambling is formed via isomerization of the substrate by inversive anion exchange and a successive ks pathway with configurational inversion.Such a retained product was not detected in the acetolysis of threo-1-methyl-2-phenylpropyltoluene-p-sulphonate with no electron withdrawing substituent.