3483-11-2 Usage
Description
Lithium acetoacetate is a chemical compound with the formula LiC5H7O3, which is a derivative of acetoacetic acid. It is a white crystalline solid that is soluble in water and has various applications in different industries due to its unique properties.
Uses
Used in Pharmaceutical Industry:
Lithium acetoacetate is used as a neuroprotective agent for the protection of retinal ganglion cells in rats against N-Methyl-D-aspartate (NMDA)-induced damage. This application is significant in the development of treatments for neurodegenerative diseases and conditions affecting the retina.
Used in Analytical Chemistry:
Lithium acetoacetate is used as an acetoacetate standard in the measurement of acetoacetate levels in biological samples. This is crucial for accurate quantification and analysis of acetoacetate in various research and diagnostic applications.
Used in Chemical Synthesis:
Lithium acetoacetate can be used for the preparation of sodium acetoacetate, which is another important chemical compound with various applications in the chemical and pharmaceutical industries. The versatility of lithium acetoacetate in synthesis makes it a valuable compound for researchers and chemists.
Check Digit Verification of cas no
The CAS Registry Mumber 3483-11-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,8 and 3 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3483-11:
(6*3)+(5*4)+(4*8)+(3*3)+(2*1)+(1*1)=82
82 % 10 = 2
So 3483-11-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H6O3.Li/c1-3(5)2-4(6)7;/h2H2,1H3,(H,6,7);/q;+1/p-1
3483-11-2Relevant articles and documents
Purification and structural analysis of volatile sesquiterpenes produced by Escherichia coli carrying unidentified terpene synthase genes from edible plants of the family Araliaceae
Shindo, Kazutoshi,Hattan, Jun-Ichiro,Kato, Mariko,Sato, Miho,Ito, Tomoko,Shibuya, Yurika,Watanabe, Arisa,Sugiyama, Maki,Nakamura, Yuri,Misawa, Norihiko
, p. 978 - 985 (2018)
A simple method to purify volatile sesquiterpenes from recombinant Escherichia coli was developed using the cells that carried known sesquiterpene synthase (Tps) genes ZzZss2 (ZSS2) and ZoTps1. This method was applied for the purification and structural analyses of volatile sesquiterpenes produced by E. coli cells that carried unidentified Tps genes, which were isolated from the Aralia-genus edible plants belonging to the family Araliaceae. Recombinant cells carrying each Tps gene were cultured in the two-layer medium (n-octane/TB medium), and volatile sesquiterpenes trapped in n-octane were purified through two-phase partition, silica gel column chromatography, and reversed-phase preparative high-performance liquid chromatography, if necessary. Further, their structures were confirmed by nuclear magnetic resonance, [α]D, and gas chromatography–mass spectrometry analyses. Herein, the products of E. coli cells that carried two Tps gene (named AcTps1 and AcTps2) in Araria cordata “Udo” and a Tps gene (named AeTps1) in Aralia elata “Taranoki” were studied resulting in identifying functionalities of these cryptic Tps genes.