34832-35-4Relevant academic research and scientific papers
Preparation method of sodium thioacetate and method for preparing thiolactone by using sodium thioacetate
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Paragraph 0034; 0050-0061, (2020/12/05)
The invention relates to the field of organic chemistry, and discloses a preparation method of sodium thioacetate and a method for preparing thiolactone from sodium thioacetate, which are characterized in that the method comprises the following steps: in the presence of a first solvent, reacting RONa with thioacetic acid; wherein R is an alkyl group of C1 to C4, preferably an alkyl group of C1 toC2. The method has the advantages of simple process, cheap and easily available raw materials and high product yield, and provides convenience for industrial production of sodium thioacetate. The thiolactone prepared from the sodium thioacetate prepared by the method has the advantages of high reaction yield, few side reactions and high product purity.
Catalyst- and organic solvent-free synthesis of thioacids in water
Elagawany, Mohamed,Hegazy, Lamees,Elgendy
supporting information, p. 2018 - 2021 (2019/07/03)
Thioacids and thioamino acids were synthesized in excellent yields from readily available acyl benzotriazoles and sodium hydrosulfide in water at room temperature. The new methodology features mild reaction conditions, high yields, short reaction times, and does not involve the use of organic solvents or bases. The reaction is eco-friendly, and the workup procedure is simple and does not require chromatographic separation.
Amine Induced Retardation of the Radical-Mediated Thiol-Ene Reaction via the Formation of Metastable Disulfide Radical Anions
Love, Dillon M.,Kim, Kangmin,Goodrich, John T.,Fairbanks, Benjamin D.,Worrell, Brady T.,Stoykovich, Mark P.,Musgrave, Charles B.,Bowman, Christopher N.
, p. 2912 - 2919 (2018/03/09)
The effect of amines on the kinetics and efficacy of radical-mediated thiol-ene coupling (TEC) reactions was investigated. By varying the thiol reactant and amine additive, it was shown that amines retard thiyl radical-mediated reactions when the amine is
Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission
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, (2008/06/13)
Alkoxy-modified silsesquioxane compounds are described. The alkoxy-modified silsesquioxane compounds contain an alkoxysilane group that participates in an alkoxysilane-silica reaction as a silica dispersing agent in rubber, with the release of zero to about 0.1% by weight of the rubber of volatile organic compounds (VOC), especially alcohol, during compounding and further processing. Further described are methods for making alkoxy-modified silsesquioxanes, methods for making vulcanizable rubber compounds containing alkoxy-modified silsesquioxanes, vulcanizable rubber compounds containing alkoxy-modified silsesquioxanes, and pneumatic tires comprising a component that contains alkoxy-modified silsesquioxanes.
Antibacterial β-lactam compounds
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, (2008/06/13)
Novel β-lactam compounds classified into penem compounds, a process for preparing the same and use of such β-lactam compounds are disclosed. These β-lactam compounds exhibit excellent antimicrobial activities useful as pharmaceuticals or they are important intermediates for the synthesis of compounds having antimicrobial activities.
A Convenient Preparation of Anhydrous Alkali Metal Thiocarboxylates
Kato, Shinzi,Oguri, Motohiro,Ishida, Masaru
, p. 1585 - 1590 (2007/10/02)
A series of alkali metal thiocarboxylates (1-5) were found to be readily obtained in high yields by the reaction of thiocarboxylic acids with metal hydrides (LiH, NaH, KH), and rubidium or caesium acetates, respectively.Their physical properties were disclosed. - Keywords: Lithium Thiocarboxylates, Sodium Thiocarboxylates, Potassium Thiocarboxylates, Rubidium Thiocarboxylates, Caesium Thiocarboxylates
Antibacterial agents, and 4-thio azetidinone intermediates
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, (2008/06/13)
This invention relates to 2-substituted and 2,6-disubstituted penem compounds of the formula STR1 wherein Y is hydrogen, halo or certain organic substituents and X represents certain organic substituents. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3-position is protected as by an easily removable ester protecting group. The compounds of the present invention are potent antibacterial agents or are of use as intermediates in the preparation of such agents.
2,6-Disubstituted penem compounds
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, (2008/06/13)
This invention relates to 2-substituted and 2,6-disubstituted penem compounds of the formula STR1 wherein Y is hydrogen, halo or certain organic radicals and X represents certain hetero-interrupted substituted alkyl radicals. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3-position is protected as by an easily removable ester protecting group. The compounds of the present invention are potent antibacterial agents or are of use as intermediates in the preparation of such agents.
Dithio prostaglandin derivatives
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, (2008/06/13)
Prostaglandin analogues of the formula: STR1 wherein A represents a grouping of the formula: STR2 X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R1 represents a straight- or branched-chain alkyl group containing from 4 to 10 carbon atoms, and R2 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms and cyclodextrin clathrates of such acids and esters and, when R2 represents a hydrogen atom, non-toxic salts thereof, the bonds attaching the epidithio radical to the carbon atoms in the 9- and 11-positions in the grouping of formula VA being either botn in α-configuration or both in β-configuration are disclosed. These compounds exhibit characteristic prostaglandin properties.
