34833-36-8

Upstream product

• 1461-22-9 tributyltin chloride 
• 100-47-0 benzonitrile 
• 7342-47-4 tributyltin iodide 
• 17846-68-3 azido tributyltin (IV) 

Downstream Products

• 83576-20-9 1-(2-hydroxy-1-phenylethyl)-5-phenyltetrazole 
• 83576-19-6 1-(2-hydroxy-2-phenylethyl)-5-phenyltetrazole 
• 83576-18-5 1-(2-hydroxycyclohexyl)-5-phenyltetrazole 
• 93742-44-0 (+/-)-1-(5-phenyl-2H-tetrazol-2-yl)propan-2-ol 
• 83576-17-4 1-(2-hydroxypropyl)-5-phenyltetrazole 
• 18039-45-7 2,5-diphenyl-2H-tetrazole 
• 4046-03-1 2-methyl-5-phenyl-[1,3,4]oxadiazole 
• 670-83-7 2,4-diphenyl-1H-imidazole 
• 670-83-7 NSC 167196 
• 83576-25-4 5-Phenyl-1-((E)-styryl)-1H-tetrazole 
• 83576-13-0 5-phenyl-5,6-dihydrotetrazolo<5,1-a>isoquinoline 
• 83576-24-3 1-(cyclohex-1-enyl)-5-phenyltetrazole 
• 83576-26-5 5-phenyl-1-(1-phenylvinyl)-1H-tetrazole 
• 79866-76-5 5-phenyl-1-vinyl-5H-tetrazole 

Relevant academic research and scientific papers

Tin-Catalyzed Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles: Homogeneous and Heterogeneous Procedures

The preparation of 5-substituted 1H-tetrazoles was efficiently achieved by reaction of trimethylsilylazide with nitriles using a triorganotin alkoxide precatalyst. The reaction mechanism was first investigated using a homogeneous tributyltin derivative and was explored through experimental investigations and DFT calculations. A heterogeneous version was then developed using a polymer-supported organotin alkoxide and afforded an efficient method for the preparation of tetrazoles in high yields with an easy work-up and a residual tin concentration in the desired products compatible for pharmaceutical applications (less than 10 ppm). (Figure presented.).

A new approach to the one-pot synthesis of 5-substituted 2-methyl-1,3,4-oxadiazoles from N-tributylstannyltetrazoles

A new approach to the synthesis of 5-substituted 2-methyl-1,3,4-oxadiazoles was developed.