348618-36-0Relevant academic research and scientific papers
4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as potent Src kinase inhibitors
Berger, Dan M.,Dutia, Minu,Birnberg, Gary,Powell, Dennis,Boschelli, Diane H.,Wang, Yanong D.,Ravi, Malini,Yaczko, Deanna,Golas, Jennifer,Lucas, Judy,Boschelli, Frank
, p. 5909 - 5920 (2005)
It has been previously reported that appropriately substituted 4-anilinoquinoline-3-carbonitriles are potent inhibitors of Src kinase, with biological activity in vitro and in vivo. Structural modifications to these compounds have been explored, providing
Tricyclic protein kinase inhibitors
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, (2008/06/13)
This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyro sine kinase and are antiproliferative agents.
