34877-79-7Relevant academic research and scientific papers
One-Pot Enol Silane Formation-Alkylation of Ketones with Propargyl Carboxylates Promoted by Trimethylsilyl Trifluoromethanesulfonate
Downey, C. Wade,Confair, Danielle N.,Liu, Yiqi,Heafner, Elizabeth D.
, p. 12931 - 12938 (2018/10/20)
Ketones readily undergo conversion to enol silanes in the presence of a trialkylamine base and trimethylsilyl trifluoromethanesulfonate (TMSOTf) and add to propargyl cations to yield β-alkynyl ketones. The propargyl cations are generated in the same react
Catalytic decarboxylative alkylation of β-keto acids with sulfonamides via the cleavage of carbon-nitrogen and carbon-carbon bonds
Yang, Cui-Feng,Wang, Jian-Yong,Tian, Shi-Kai
supporting information; experimental part, p. 8343 - 8345 (2011/09/16)
An efficient decarboxylative alkylation reaction of β-keto acids with N-benzylic or N-allylic sulfonamides has been developed, for the first time, through sequential cleavage of carbon-nitrogen and carbon-carbon bonds in the presence of 10 mol% of FeCl3.
Atom-economical chemoselective synthesis of 1,4-diynes and polysubstituted furans/pyrroles from propargyl alcohols and terminal alkynes
Wang, Tao,Chen, Xin-Liang,Chen, Li,Zhan, Zhuang-Ping
supporting information; experimental part, p. 3324 - 3327 (2011/09/12)
Under different conditions, the reaction of propargyl alcohols and terminal alkynes leads to the selective formation of 1,4-diynes and polysubstituted furans/pyrroles. Water is the only byproduct in the selective synthesis of 1,4-diynes and pyrroles, and
A novel indium-catalyzed three-component reaction: General and efficient one-pot synthesis of substituted pyrroles
Lin, Min,Hao, Lu,Ma, Rui-Da,Zhan, Zhuang-Ping
experimental part, p. 2345 - 2351 (2010/11/04)
A convenient and general approach towards the synthesis of substituted pyrroles from propargylic acetates, silyl enol ethers, and primary amines was described. This novel transformation was catalyzed by indium trichloride in a one-pot synthesis, and high
Copper(II) triflate-catalyzed nucleophilic substitution of propargylic acetates with enoxysilanes. A straightforward synthetic route to polysubstituted furans
Zhan, Zhuang-Ping,Wang, Shao-Pei,Cai, Xu-Bin,Liu, Hui-Juan,Yu, Jing-Liang,Cui, Yuan-Yuan
, p. 2097 - 2102 (2008/09/18)
A novel and efficient procedure for the synthesis of γ-alkynyl ketones by the nucleophilic substitution of propargylic acetates with enoxysilanes in the presence of a catalytic amount of Copper(II) triflate, has been developed. The substitution reaction c
FeCl3-catalyzed nucleophilic substitution of propargylic acetates with enoxysilanes
Zhan, Zhuang-Ping,Cai, Xu-Bin,Wang, Shao-Pei,Yu, Jing-Liang,Liu, Hui-Juan,Cui, Yuan-Yuan
, p. 9838 - 9841 (2008/03/28)
(Chemical Equation Presented) An efficient FeCl3-catalyzed substitution reaction of propargylic acetates with enoxysilanes under mild conditions to afford corresponding γ-alkynyl ketones has been developed. The substitution reaction is followed
Generation of organotantalum reagents and conjugate addition to enones
Shibata, Ikuya,Kano, Takeyoshi,Kanazawa, Nobuaki,Fukuoka, Shoji,Baba, Akio
, p. 1389 - 1392 (2007/10/03)
A superior method of conjugate allylation: The transmetalation of allyltin compounds with TaCl5 yielded active tantalum reagents for conjugate addition to enones. Even bulky allyl moieties could be introduced to enones in this manner (see scheme). Both cyclic and acyclic enones reacted facilely under extremely mild conditions.
Boron Trifluoride Etherate Mediated 1,4-Addition of (1-Alkynyl)diisopropoxyboranes to α,β-Unsaturated Ketones. A Convenient New Route to 3-Alkynyl Ketone Synthesis
Fujishima, Hiroaki,Takada, Ei-ichi,Hara, Shoji,Suzuki, Akira
, p. 695 - 698 (2007/10/02)
In the presence of BF3 etherate, (1-alkynyl)diisopropoxyboranes react with α,β-unsaturated ketones to give 1,4-addition products selectively in good yields.
