349-56-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Methoxy-5-(trifluoromethyl)phenol is used as a synthesis intermediate for the development of new pharmaceuticals. Its unique structure allows for the creation of compounds with potential therapeutic effects, contributing to the advancement of medicinal chemistry.
Used in Agricultural Industry:
In agriculture, 3-Methoxy-5-(trifluoromethyl)phenol is used as an ingredient in various products due to its potential antibacterial and antifungal properties. These properties can be harnessed to develop new pesticides or fungicides, enhancing crop protection and yield.
Used in Material Science:
3-Methoxy-5-(trifluoromethyl)phenol is utilized in material science for the development of new materials with specific properties. Its unique structure can contribute to the creation of materials with enhanced characteristics, such as improved stability or reactivity.
Used in Antioxidant Applications:
3-Methoxy-5-(trifluoromethyl)phenol is used as an antioxidant in various commercial products. Its potential antioxidant properties can help prevent oxidative damage and extend the shelf life of products, making it a valuable ingredient in the food and cosmetic industries.
Further studies are required to fully understand the potential uses and effects of 3-Methoxy-5-(trifluoromethyl)phenol, ensuring its safe and effective application across different industries.

Upstream product

• 349-55-3 5-(trifluoromethyl)-m-anisidine 
• 67-56-1 methanol 
• 172333-87-8 3-fluoro-5-(trifluoromethyl)phenol 

Downstream Products

• 440-94-8 1-methoxy-2,5-bis-(4-nitro-benzoyloxy)-3-trifluoromethyl-benzene 
• 859739-30-3 5-benzyloxy-2,3-dimethoxy-benzoic acid methyl ester 
• 116530-57-5 5-hydroxy-2,3-dimethoxy-benzoic acid 
• 5981-38-4 2,5-dihydroxy-3-methoxybenzoic acid 
• 35562-95-9 5-benzyloxy-2-hydroxy-3-methoxy-benzoic acid methyl ester 
• 99179-82-5 2,5-dihydroxy-3-methoxy-benzoic acid methyl ester 
• 369-99-3 4-nitro-benzoic acid-(5-methoxy-3-trifluoromethyl-phenyl ester) 
• 344-28-5 2-methoxy-6-trifluoromethyl-hydroquinone 
• 454-68-2 5-(trifluoromethyl)phenyl-1,3-diol 

Relevant academic research and scientific papers

Catalytic SNAr Hydroxylation and Alkoxylation of Aryl Fluorides

Nucleophilic aromatic substitution (SNAr) is a powerful strategy for incorporating a heteroatom into an aromatic ring by displacement of a leaving group with a nucleophile, but this method is limited to electron-deficient arenes. We have now established a reliable method for accessing phenols and phenyl alkyl ethers via catalytic SNAr reactions. The method is applicable to a broad array of electron-rich and neutral aryl fluorides, which are inert under classical SNAr conditions. Although the mechanism of SNAr reactions involving metal arene complexes is hypothesized to involve a stepwise pathway (addition followed by elimination), experimental data that support this hypothesis is still under exploration. Mechanistic studies and DFT calculations suggest either a stepwise or stepwise-like energy profile. Notably, we isolated a rhodium η5-cyclohexadienyl complex intermediate with an sp3-hybridized carbon bearing both a nucleophile and a leaving group.

Inhibitors of α4 mediated cell adhesion

The present invention relates to a pharmaceutical composition comprising as an active ingredient a compound of formula (I), wherein Ring A is an aromatic or a heterocyclic ring; Q is a bond, carbonyl, lower alkylene, lower alkenylene, —O-(lower alkylene)-, etc.; n is 0, 1 or 2; Z is oxygen or sulfur, W is oxygen, sulfur, —CH═CH—, —NH— or —N═CH—; R1, R2and R3are the same or different and are hydrogen, halogen, hydroxyl, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted lower alkoxy group, a substituted or unsubstituted amino group, etc.; R4is tetrazolyl, carboxyl group, amide or ester; R5is hydrogen, nitro, amino, hydroxyl, lower alkanoyl, lower alkyl etc.; R6is selected from (a) a substituted or unsubstituted phenyl group, (b) a substituted or unsubstituted pyridyl group, (c) a substituted or unsubstituted thienyl group, (d) a substituted or unsubstituted benzofuranyl group, etc.; or a pharmaceutically acceptable salt thereof.