349-65-5Relevant articles and documents
Method for preparing 4-bromo-2-methoxy-5-trifluoromethyl benzaldehyde
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, (2022/04/03)
The invention provides a method for preparing 4-bromo-2-methoxy-5-(trifluoromethyl) benzaldehyde, and belongs to the field of synthesis processes. The method comprises the following steps: carrying out formylation reaction on a compound VI, so as to obtain the 4-bromo-2-methoxy-5-trifluoromethyl benzaldehyde. The method for preparing the 4-bromine-2-methoxy-5-trifluoromethyl benzaldehyde has the advantages of easily available raw materials, mild reaction conditions, simple steps, low cost, safety, no toxicity and easiness in large-scale production, can obviously improve the total yield and purity of the target product 4-bromine-2-methoxy-5-trifluoromethyl benzaldehyde, and has wide application prospects.
ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS
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Page/Page column 10; 15, (2014/06/24)
The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R' is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R" and R"' are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.
Palladium-catalyzed silane/siloxane reductions in the one-pot conversion of nitro compounds into their amines, hydroxylamines, amides, sulfonamides, and carbamates
Rahaim Jr., Ronald J.,Maleczka Jr., Robert E.
, p. 3316 - 3340 (2008/09/17)
A combination of palladium(II) acetate, aqueous potassium fluoride, and polymethylhydrosiloxane (PMHS) facilitates the room-temperature reduction of aromatic nitro compounds to anilines. These reactions tend to be quick (30 min), high-yielding, and tolerate a range of other functional groups. Replacement of PMHS/KF with triethylsilane allows for the reduction of aliphatic nitro compounds to their corresponding hydroxylamines. Depending on the substrate, both conditions can allow for the in situ conversion of the product amines into amides, sulfonamides, and carbamates. Georg Thieme Verlag Stuttgart.