34906-84-8

Usage

Uses

Used in the Fragrance Industry:
ETHYL 4-ISO-PROPYLBENZOYLFORMATE is used as a fragrance ingredient for its sweet, floral, and fruity scent, enhancing the aroma profiles of perfumes, soaps, and other scented goods.
Used in the Flavor Industry:
In the flavor industry, ETHYL 4-ISO-PROPYLBENZOYLFORMATE is used as a flavoring agent to impart a unique taste to food and beverages, contributing to the overall sensory experience of these products.
Used in Cosmetic and Personal Care Products:
ETHYL 4-ISO-PROPYLBENZOYLFORMATE is used as a key component in the formulation of various cosmetic and personal care products, where its scent and properties contribute to the product's appeal and effectiveness.

InChI:InChI=1/C13H16O3/c1-4-16-13(15)12(14)11-7-5-10(6-8-11)9(2)3/h5-9H,4H2,1-3H3

Upstream product

• 349138-85-8 N-(4-isopropylphenyl)-4-methylbenzenesulfonamide 
• 2999-46-4 Ethyl isocyanoacetate 
• 98-82-8 Isopropylbenzene 
• 4755-77-5 Ethyl oxalyl chloride 
• 64-17-5 ethanol 
• 51208-83-4 2-(4-isopropylphenyl)-2-oxoacetic acid 

Downstream Products

• 1223562-84-2 (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl [4-(1-methylethyl)phenyl](oxo)acetate 
• 77053-73-7 (1S,2R)-1-(4-Isopropyl-phenyl)-cyclopropane-1,2-dicarboxylic acid diethyl ester 
• 77053-84-0 (1R,2S)-1-(4-Isopropyl-phenyl)-cyclopropane-1,2-dicarboxylic acid 
• 77053-59-9 Brom-(4-isopropyl-phenyl)-essigsaeure-ethylester 
• 77053-89-5 1-(p-Cumyl)-1,2-cyclopropan-dicarboximid 
• 86215-47-6 1-(p-Cumyl)-3-azabicyclo<3.1.0>hexan 
• 6283-47-2 ethyl hydroxy(4-isopropylphenyl)acetate 

Relevant academic research and scientific papers

Destruction and Construction: Application of Dearomatization Strategy in Aromatic Carbon-Nitrogen Bond Functionalization

The formation of carbon-carbon bonds through the functionalization of aromatic carbon-nitrogen bonds is a highly attractive synthetic strategy in the synthesis of aromatic molecules. In this paper, we report a novel aromatic carbon-nitrogen bond functionalization reaction by using a simple dearomatization strategy. Through this process para-substituted anilines serve as a potential aryl source in the construction of a range of functionalized aromatic molecules, such as quaternary carbon centers, α-keto esters, and aldehydes.

1-Aryl-3-azabicyclohexanes, a New Series of Nonnarcotic Analgesic Agents

A series of 1-aryl-3-azabicyclohexanes was synthesized by hydride reduction of 1-arylcyclopropanedicarboximides.Hydroxyphenyl analogues 20, 22, and 24 were prepared by EtSNa-DMF ether cleavage of the corresponding methoxyphenyl analogues 2m, 2n, and 23, respectively, with the secondary amines 20 and 22 going through the N-formyl intermediates 19 and 21.The p-ethoxy analogue 26 was obtained by O-ethylation of 19, followed by base hydrolysis of the amide 25.The greatest analgesic potency in mouse writhing and rat paw-pain assays was observed for para-substituted compounds.Bicifadine, 1-(4-methylphenyl)-3-azabicyclohexane (2b), was the most potent member of the series and is presently undergoing clinical trials in man.Analgesic activity of 2b is limited to the (+) enantiomer 2v, which has the 1R,5S absolute configuration as determined by single-crystal X-ray analysis.The N-methyl analogue (27d) of 2b showed significant analgesic potency, whereas the N-allyl (27a), N-(cyclopropylmethyl) (27b), and N-(n-hexyl) (27c) analogues were inactive.Bicifadine (2b) showed a nonnarcotic profile different from analogous azabicycloalkane and 3-phenylpyrrolidine analgesics.