349116-86-5Relevant academic research and scientific papers
Design and synthesis of N-methylpyrimidone derivatives as HIV-1 integrase inhibitors
Wang, Yujie,Rong, Jie,Zhang, Bin,Hu, Liming,Wang, Xiaoli,Zeng, Chengchu
, p. 735 - 741 (2015)
A series of novel β-diketo derivatives which combined the virtues of dihydroxypyrimidine carboxamide derived from the evolution of DKA and polyhydroxylated aromatics moieties, were designed and synthesized as potential HIV-1 integrase (IN) inhibitors and
Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor
Yang, Leifu,Xu, Xuemei,Huang, Yali,Zhang, Bin,Zeng, Chengchu,He, Hongqiu,Wang, Cunxin,Hu, Liming
supporting information; experimental part, p. 5469 - 5471 (2010/12/24)
(E)-N-[3-(4-Cinnamoylpiperazin-1-yl)propyl]-3,4-dihydroxybenzamide and (E)-N-[3-(4-cinnamoylpiperazin-1-yl)propyl]-3,4,5-trihydroxybenzamide were designed and synthesized as potential HIV-1 integrase inhibitors and evaluated their inhibition to the strand
