349118-82-7Relevant academic research and scientific papers
Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)
Flanagan, Jack U.,Atwell, Graham J.,Heinrich, Daniel M.,Brooke, Darby G.,Silva, Shevan,Rigoreau, Laurent J.M.,Trivier, Elisabeth,Turnbull, Andrew P.,Raynham, Tony,Jamieson, Stephen M.F.,Denny, William A.
, p. 967 - 977 (2014/02/14)
Inhibitors of the aldo-keto reductase enzyme AKR1C3 are of interest as potential drugs for leukemia and hormone-related cancers A series of non-carboxylate morpholino(phenylpiperazin-1-yl)methanones were prepared by palladium-catalysed coupling of substit
Achieving functional group diversity in parallel synthesis: solution-phase synthesis of a library of ureas, carbamates, thiocarbamates, and amides using carbamoylimidazolium salts
Grzyb, Justyna A.,Batey, Robert A.
, p. 5279 - 5282 (2008/12/21)
A convenient protocol for the parallel solution-phase synthesis of a library of thiocarbamates, ureas, carbamates, and amides from carbamoylimidazolium salts has been developed. The crystalline carbamoylimidazolium salts are readily synthesized from secon
