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349125-08-2

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349125-08-2 Usage

General Description

N-(5-Chloropyridin-2-yl)oxalaMic acid ethyl ester is a chemical compound with the molecular formula C10H8ClNO4. It is an ethyl ester derivative of oxalamic acid, containing a chloropyridine functional group. N-(5-Chloropyridin-2-yl)oxalaMic acid ethyl ester has potential applications in the field of medicinal chemistry and drug discovery, as it may exhibit biological activity due to its structural features. It is important to handle this compound with caution and adhere to proper safety protocols when working with it in a laboratory setting, as its properties and potential hazards should be taken into consideration.

Check Digit Verification of cas no

The CAS Registry Mumber 349125-08-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,9,1,2 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 349125-08:
(8*3)+(7*4)+(6*9)+(5*1)+(4*2)+(3*5)+(2*0)+(1*8)=142
142 % 10 = 2
So 349125-08-2 is a valid CAS Registry Number.

349125-08-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(5-chloro-pyridin-2-yl)-oxalamic acid ethyl ester

1.2 Other means of identification

Product number -
Other names n-(5-chloropyridin-2-yl)oxalamicacidethylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:349125-08-2 SDS

349125-08-2Relevant articles and documents

Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors

Harada, Shigeyoshi,Kobayakawa, Takuya,Konno, Kiju,Kuwata, Takeo,Masuda, Ami,Matsushita, Shuzo,Ohashi, Nami,Takahashi, Kohei,Tamamura, Hirokazu,Tsuji, Kohei,Yoshimura, Kazuhisa

, (2022/01/24)

Several small molecule CD4 mimics, which inhibit the interaction of gp120 with CD4, have been developed. Original CD4 mimics such as NBD-556, which has an aromatic ring, an oxalamide linker and a piperidine moiety, possess significant anti-HIV activity bu

Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase

Winterton, Sarah E.,Capota, Emanuela,Wang, Xiaoyu,Chen, Hong,Mallipeddi, Prema L.,Williams, Noelle S.,Posner, Bruce A.,Nijhawan, Deepak,Ready, Joseph M.

, p. 5199 - 5221 (2018/06/13)

Stearoyl-CoA desaturase (SCD) catalyzes the first step in the conversion of saturated fatty acids to unsaturated fatty acids. Unsaturated fatty acids are required for membrane integrity and for cell proliferation. For these reasons, inhibitors of SCD represent potential treatments for cancer. However, systemically active SCD inhibitors result in skin toxicity, which presents an obstacle to their development. We recently described a series of oxalic acid diamides that are converted into active SCD inhibitors within a subset of cancers by CYP4F11-mediated metabolism. Herein, we describe the optimization of the oxalic acid diamides and related N-acyl ureas and an analysis of the structure-activity relationships related to metabolic activation and SCD inhibition.

LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS

-

Page/Page column 104, (2010/02/08)

The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein M is a non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trysin-like serine proteases, specifically factor Xa.

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