349620-39-9

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 71962-74-8 Ethyl nipecotate 

Downstream Products

• 1257268-66-8 3-(diphenylmethylene)-1-(phenylsulfonyl)piperidine 
• 1355995-59-3 3-[bis(4-fluorophenyl)methylene]-1-(phenylsulfonyl)piperidine 
• 1355995-60-6 3-(di-p-tolylmethylene)-1-(phenylsulfonyl)piperidine 
• 1355995-75-3 5-(methoxydiphenylmethyl)-1-(phenylsulfonyl)-1,2,3,6-tetrahydropyridine 
• 1355995-74-2 C₂₅H₂₅NO₃S 
• 1355995-77-5 C₂₅H₂₃F₂NO₃S 
• 1355995-62-8 3-(diphenylmethylene)-1-(phenylsulfonyl)piperidine-2-carbonitrile 
• 1355995-76-4 C₂₅H₂₂N₂O₂S 
• 1355995-63-9 3-[bis(4-fluorophenyl)methylene]-1-(phenylsulfonyl)piperidine-2-carbonitrile 
• 1355995-64-0 3-(di-p-tolylmethylene)-1-(phenylsulfonyl)piperidine-2-carbonitrile 
• 1355995-67-3 2-allyl-3-(diphenylmethylene)-1-(phenylsulfonyl)piperidine 
• 1355995-68-4 2-allyl-3-[bis(4-fluorophenyl)methylene]-1-(phenylsulfonyl)piperidine 
• 1355995-69-5 2-allyl-3-(di-p-tolylmethylene)-1-(phenylsulfonyl)piperidine 
• 1355995-79-7 methyl 3-(diphenylmethylene)-1-(phenylsulfonyl)piperidine-2-carboxylate 

Relevant academic research and scientific papers

Regioselective synthesis of 2-substituted 3-diarylmethylenylpiperidines

A simple three-step synthetic routes toward 2-substituted 3-diarylmethylenylpiperidines 7 (Y = CN) and 8 (Y = allyl) starting with 3-diarylmethylenylpiperidines 9 is described. The process was carried out by the bromomethoxylation of skeleton 9 with NBS i

N-substituted piperidines and their use as pharrmaceuticals

The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.