34981-11-8Relevant articles and documents
A simple and efficient route for preparing 2,3,5,6-tetraaminopyridine hydrochloride salt
Wang, Yanhong,Hu, Zhen,Meng, Xiangli,Jing, Jiehui,Song, Yuanjun,Zhang, Chunhua,Huang, Yudong
, p. 1652 - 1659 (2009)
A simple and efficient route for preparing 2,3,5,6-tetraaminopyridine hydrochloride salt (TAP-3HCl.H2O) was introduced in this paper. The title compound was synthesized, as usual, in two steps (nitration and hydrogenation) with a total yield of
Nitration method for preparing 2, 6-diamido-3, 5-binitro pyridine by ultrafine zeolite-based micro-channel reaction
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Page/Page column 6-9, (2019/03/08)
The invention provides a nitration method for preparing 2, 6-diamido-3, 5-binitro pyridine by ultrafine zeolite-based micro-channel reaction. The nitration method includes the steps: heating and uniformly mixing crushed sodium amide, decahydronaphthalene and p-toluidine, performing microwave heating reaction on mixture and pyridine by a Y-shaped micro-channel reactor, and filtering and recrystallizing the mixture and the pyridine to obtain 2, 6-diamido pyridine; blowing ultrafine HZSM-5 catalysts into an outlet channel of the Y-shaped micro-channel reactor, placing the modified Y-shaped micro-channel reactor into an ice-water bath, leading the 2, 6-diamido pyridine and dichloromethane solution containing nitrogen pentoxide into the Y-shaped micro-channel reactor, accelerating flow and rapidly increasing temperature to reach reaction temperature to obtain a 2, 6-diamido-3, 5-binitro pyridine crude product; secondarily recrystallizing, filtering and drying the 2, 6-diamido-3, 5-binitro pyridine crude product, adding the crude product into distilled water, boiling the distilled water and performing dimethyl sulfoxide secondary crystallization to obtain the 2, 6-diamido-3, 5-binitro pyridine with high yield and purity.
Aminonitropyridines and their N-oxides
Hollins, Richard A.,Merwin, Lawrence H.,Nissan, Robin A.,Wilson, William S.,Gilardi, Richard
, p. 895 - 904 (2007/10/03)
2,6-Diamino-3,5-dinitropyridine 1-oxide has been prepared by mixed acid nitration of 2,6-diaminopyridine, followed by oxidation using hydrogen peroxide in acetic acid. 3,5-Dinitro-2,4,6-triaminopyridine has been prepared by oxidative amination of 2-chloro-3,5-dinitropyridine or 2,6-diamino-3,5-dinitropyridine using potassium permanganate in liquid ammonia, or by "vicarious nucleophilic amination" of 2,6-diamino-3,5-dinitropyridine using hydroxylamine in aqueous potassium hydroxide. 3,5-Dinitro-2,4,6-triaminopyridine 1-oxide has been prepared by oxidation of 3,5-dinitro-2,4,6-triaminopyridine using hydrogen peroxide in acetic acid, and by "vicarious nucleophilic amination" of 2,6-diamino-3,5-dinitropyridine 1-oxide. Nmr spectroscopy and single crystal X-ray diffraction studies have shown that these compounds have the planar structures and intra- and inter-molecular hydrogen bonding necessary to confer on the materials the high density, the thermal and chemical stability, and the explosive insensitivity required for new insensitive energetic materials.