34998-70-4Relevant academic research and scientific papers
Platinum-catalyzed oxoarylations of ynamides with nitrones
Bhunia, Sabyasachi,Chang, Chin-Jung,Liu, Rai-Shung
supporting information, p. 5522 - 5525,4 (2020/10/15)
A new platinum-catalyzed oxoarylation of ynamides with nitrones is reported. Cascade sequences for the synthesis of indolin-2-ones via NaBH 3CN reduction in situ of the initially formed oxoarylation products are also developed.
Microwave-assisted sequential amide bond formation and intramolecular amidation: A rapid entry to functionalized oxindoles
Poondra, Rajamohan R.,Turner, Nicholas J.
, p. 863 - 866 (2007/10/03)
(Chemical Equation Presented) A general method has been developed for the synthesis of N-substituted oxindoles. The two-step process involves initial microwave-assisted amide bond formation between 2-halo-arylacetic acids and various alkylamines and anilines, followed by a palladium-catalyzed intramolecular amidation under aqueous conditions. In the case of alkylamines, the procedure can be carried out as a one-pot process without isolation of the intermediate amide.
